Three Cases of Previous Smokers with Rheumatoid Arthritis Who Did Not Respond to Tumor Necrosis Factor Inhibitors Were Treated Successfully with an Anti-Interleukin-6 Receptor Antibody
المؤلف
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-01-14
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
We report three cases of previous smokers who did not respond to TNF inhibitors but who responded successfully to an anti-interleukin-6 receptor antibody (tocilizumab (TCZ)).
Case 1 is a 63-year-old woman whose smoking index was 200 and had been complaining of polyarthralgia since 1996.
She started treatment with etanercept due to high disease activity, but her DAS28-CRP was 4.2.
She was therefore switched to TCZ, which dramatically improved her symptoms; her DAS28-CRP had decreased to 2.1.
Case 2 is a 64-year-old man whose smoking index was 1600 and had been complaining of polyarthralgia since 2006.
Because his DAS28-CRP score increased over time to 5.9, etanercept and adalimumab were added sequentially, but he showed no response over the course of two years.
The patient was therefore switched to TCZ, which dramatically improved his symptoms: his DAS28-CRP decreased to 2.7.
Case 3 is a 48-year-old woman whose smoking index was 560 and had been complaining of pain in both knee joints since 2001.
She was treated with adalimumab due to high disease activity but showed no response over the course of 1.5 years.
The patient was therefore switched to TCZ, and her DAS28-CRP decreased to 1.8.
An IL-6 blockade might be suitable for treating these 3 cases of previous smokers.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Iwata, Yasuo. 2015. Three Cases of Previous Smokers with Rheumatoid Arthritis Who Did Not Respond to Tumor Necrosis Factor Inhibitors Were Treated Successfully with an Anti-Interleukin-6 Receptor Antibody. Case Reports in Rheumatology،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1059985
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Iwata, Yasuo. Three Cases of Previous Smokers with Rheumatoid Arthritis Who Did Not Respond to Tumor Necrosis Factor Inhibitors Were Treated Successfully with an Anti-Interleukin-6 Receptor Antibody. Case Reports in Rheumatology No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1059985
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Iwata, Yasuo. Three Cases of Previous Smokers with Rheumatoid Arthritis Who Did Not Respond to Tumor Necrosis Factor Inhibitors Were Treated Successfully with an Anti-Interleukin-6 Receptor Antibody. Case Reports in Rheumatology. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1059985
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1059985
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر