Cd30+ anaplastic large cell lymphoma in leukemic phase : a case report

الملخص EN

Patients with Ki (CD30) positive anaplastic large cell lymphoma occasionally have rare circulating lymphoma cells.

This report describes a case of anaplastic large cell lymphoma with prominent leukemic phase.

A 61 years old man presented with widespread anaplastic large cell lymphoma involving lymph nodes, skin, peripheral blood, and bone marrow.

His white blood count was 241,500/mm with 82% lymphoma cells.

The circulating neoplastic cells were large and had irregular nuclei, multiple small nucleoli, and multiple clear cytoplasmic vacuoles.

This case illustrates that anaplastic large cell lymphoma may have a marked leukemic phase of large anaplastic cells.