The Association of Serum IL-33 and sST2 with Breast Cancer
المؤلفون المشاركون
Yang, Zhi-Ping
Ling, Dan-Yan
Xie, Yong-Hong
Wu, Wan-Xin
Li, Jin-Rui
Jiang, Jin
Zheng, Jia-Lian
Fan, Yao-Hua
Zhang, Ye
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-09-20
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Breast cancer is one of the most common malignant diseases in women.
The main cause of death from breast cancer is its metastases at distant sites in the body.
Interleukin-33 (IL-33) is a cytokine of the IL-1 family and found overexpressed in various cancers.
The aim of the present study was to explore the association of serum IL-33 and sST2 with breast cancer.
Here, the serum levels of Interleukin-33 (IL-33) and sST2 were found significantly higher in breast cancer patients than in healthy volunteers.
Serum levels of vascular endothelial growth factor (VEGF), metalloproteinase-11 (MMP-11), and platelet-derived growth factor-C (PDGF-C) were also greater in breast cancer patients compared to healthy volunteers.
We found that serum levels of IL-33 or sST2 were positively correlated with the serum levels of VEGF, MMP-11, and PDGF-C.
Moreover, breast cancer dataset downloaded from The Cancer Genome Atlas showed that patients with higher level of MMP-11 or PDGF-C expression had shorter survival time than those with lower level of these proteins.
In conclusion, IL-33 and sST2 may serve as noninvasive diagnosis markers for breast cancer.
IL-33 and sST2 were significantly associated with MMP-11 or PDGF-C which indicated poor prognosis of breast cancer patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yang, Zhi-Ping& Ling, Dan-Yan& Xie, Yong-Hong& Wu, Wan-Xin& Li, Jin-Rui& Jiang, Jin…[et al.]. 2015. The Association of Serum IL-33 and sST2 with Breast Cancer. Disease Markers،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1060965
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yang, Zhi-Ping…[et al.]. The Association of Serum IL-33 and sST2 with Breast Cancer. Disease Markers No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1060965
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yang, Zhi-Ping& Ling, Dan-Yan& Xie, Yong-Hong& Wu, Wan-Xin& Li, Jin-Rui& Jiang, Jin…[et al.]. The Association of Serum IL-33 and sST2 with Breast Cancer. Disease Markers. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1060965
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1060965
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر