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Increased Serum Interleukin-9 Levels in Rheumatoid Arthritis and Systemic Lupus Erythematosus: Pathogenic Role or Just an Epiphenomenon?
المؤلفون المشاركون
Pitta, Ivan da Rocha
Gonçalves, Sayonara Maria Calado
Marques, Claudia Diniz Lopes
Cavalcanti, Mariana Brayner
Cardoso, Pablo Ramon Gualberto
Mariz, Henrique de Ataide
Rego, Moacyr Jesus Barreto de Melo
da Rocha Junior, Laurindo Ferreira
Pitta, Maira Galdino da Rocha
Dantas, Andréa Tavares
Duarte, Ângela Luzia Branco Pinto
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-05-19
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
The purpose of this paper was to evaluate the levels of IL-9 in patients with SLE and RA compared with controls and the association of IL-9 levels with clinical and laboratory parameters.
IL-9 levels were assessed in 117 SLE patients, 67 RA patients, and 24 healthy controls by ELISA.
Clinical and laboratory parameters were recorded.
The IL-9 serum levels were significantly higher in RA patients (4,77 ± 3,618 pg/mL) and in SLE patients (12,26 ± 25,235 pg/mL) than in healthy individuals (1,22 ± 0,706 pg/mL) ( p < 0,001 ) .
In SLE patients, there were no statistically significant associations or correlations between the levels of IL-9 and SLEDAI or other clinical and laboratorial parameters, with the exception of disease time, which showed a statistically significant negative correlation with IL-9 levels ( r = - 0,1948 ; p = 0,0378 ) .
In RA patients, no association or statistically significant correlation was observed with disease duration, DAS28, HAQ, rheumatoid factor positivity, or erosions on radiography.
These data demonstrated increased serum levels of IL-9 in SLE and RA patients, but further studies are needed to clarify the precise role of this cytokine and its potential use as therapeutic target.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dantas, Andréa Tavares& Marques, Claudia Diniz Lopes& da Rocha Junior, Laurindo Ferreira& Cavalcanti, Mariana Brayner& Gonçalves, Sayonara Maria Calado& Cardoso, Pablo Ramon Gualberto…[et al.]. 2015. Increased Serum Interleukin-9 Levels in Rheumatoid Arthritis and Systemic Lupus Erythematosus: Pathogenic Role or Just an Epiphenomenon?. Disease Markers،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1060966
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dantas, Andréa Tavares…[et al.]. Increased Serum Interleukin-9 Levels in Rheumatoid Arthritis and Systemic Lupus Erythematosus: Pathogenic Role or Just an Epiphenomenon?. Disease Markers No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1060966
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dantas, Andréa Tavares& Marques, Claudia Diniz Lopes& da Rocha Junior, Laurindo Ferreira& Cavalcanti, Mariana Brayner& Gonçalves, Sayonara Maria Calado& Cardoso, Pablo Ramon Gualberto…[et al.]. Increased Serum Interleukin-9 Levels in Rheumatoid Arthritis and Systemic Lupus Erythematosus: Pathogenic Role or Just an Epiphenomenon?. Disease Markers. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1060966
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1060966
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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