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The Apolipoprotein BApolipoprotein A-I Ratio as a Potential Marker of Plasma Atherogenicity
المؤلفون المشاركون
Kaneva, Anastasiya M.
Potolitsyna, Natalya N.
Bojko, Evgeny R.
Odland, Jon Ø.
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-23
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
The apolipoprotein (apo) B/apoA-I ratio represents the balance between apoB-rich atherogenic particles and apoA-I-rich antiatherogenic particles, and this ratio is considered to be a marker of cardiovascular risk.
Although many studies have demonstrated the importance of the apoB/apoA-I ratio in predicting the presence or absence of cardiovascular disease, less is known about apoB/apoA-I ratio as a marker of plasma atherogenicity.
Methods.
A total of 157 normolipidemic men aged 20–59 years were included in the study.
The plasma levels of total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), apoA-I, apoB, and apoE were determined after a 12 h fasting period.
Results.
The median of the apoB/apoA-I ratio in the studied normolipidemic subjects was 0.52, with values ranging from 0.19 to 2.60.
The percentage of subjects with the apoB/apoA-I ratio exceeding 0.9 (the accepted risk value of cardiovascular disease) was 19.1%.
The subjects with apoB/apoA-I>0.9 were characterized by higher TG levels and atherogenic index of plasma (AIP) and lower values of ratio of low-density lipoprotein cholesterol (LDL-C) to apoB (LDL-C/apoB) and apoE levels compared with men with apoB/apoA-I<0.9.
Conclusion.
Despite normolipidemia, the subjects with the unfavorable apoB/apoA-I ratio had more atherogenic lipid profile.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kaneva, Anastasiya M.& Potolitsyna, Natalya N.& Bojko, Evgeny R.& Odland, Jon Ø.. 2015. The Apolipoprotein BApolipoprotein A-I Ratio as a Potential Marker of Plasma Atherogenicity. Disease Markers،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1060987
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kaneva, Anastasiya M.…[et al.]. The Apolipoprotein BApolipoprotein A-I Ratio as a Potential Marker of Plasma Atherogenicity. Disease Markers No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1060987
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kaneva, Anastasiya M.& Potolitsyna, Natalya N.& Bojko, Evgeny R.& Odland, Jon Ø.. The Apolipoprotein BApolipoprotein A-I Ratio as a Potential Marker of Plasma Atherogenicity. Disease Markers. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1060987
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1060987
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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