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Cryoglobulinaemia in Egyptian Patients with Extrahepatic Cutaneous Manifestations of Chronic Hepatitis C Virus Infection
المؤلفون المشاركون
Hegab, Doaa Salah
Sweilam, Mohammed Abd El Rahman
المصدر
Dermatology Research and Practice
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-29
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Hepatitis C is a global major health problem with extremely variable extrahepatic manifestations.
Mixed cryoglobulinaemia (MC) shows a striking association with hepatitis C virus (HCV) infection, and it is sometimes asymptomatic.
The skin is a frequently involved target organ in MC.
Objective.
To investigate the prevalence of cryoglobulinaemia in a sample of Egyptian patients with cutaneous manifestations of chronic HCV infection and to correlate its presence with clinical criteria and liver function tests.
Methods.
One hundred and eighteen patients with skin manifestations of chronic compensated hepatitis C were included.
Venous blood was tested for liver function tests and serum cryoglobulins.
Results.
Twelve patients (10.169%) were positive for serum cryoglobulins (2 with pruritus, 4 with vasculitic lesions, 3 with livedo reticularis, one with oral lichen, one with chronic urticaria, and another with Schamberg’s disease).
Vasculitic lesions and livedo reticularis of the legs showed higher prevalence in cryoglobulin-positive than in cryoglobulin-negative patients.
Presence of serum cryoglobulins did not relate to patients’ demographic or laboratory findings.
Conclusions.
Fortunately, MC is not markedly prevalent among Egyptians with cutaneous lesions of chronic hepatitis C, and cryopositivity was commonly, but not exclusively, detected with cutaneous vasculitis and livedo reticularis.
Laboratory testing for cryoglobulins in every HCV patient is advisable for earlier MC detection and management.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hegab, Doaa Salah& Sweilam, Mohammed Abd El Rahman. 2015. Cryoglobulinaemia in Egyptian Patients with Extrahepatic Cutaneous Manifestations of Chronic Hepatitis C Virus Infection. Dermatology Research and Practice،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1061095
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hegab, Doaa Salah& Sweilam, Mohammed Abd El Rahman. Cryoglobulinaemia in Egyptian Patients with Extrahepatic Cutaneous Manifestations of Chronic Hepatitis C Virus Infection. Dermatology Research and Practice No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1061095
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hegab, Doaa Salah& Sweilam, Mohammed Abd El Rahman. Cryoglobulinaemia in Egyptian Patients with Extrahepatic Cutaneous Manifestations of Chronic Hepatitis C Virus Infection. Dermatology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1061095
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1061095
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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