Five-Year Retrospective Review of Acute Generalized Exanthematous Pustulosis
المؤلفون المشاركون
Thienvibul, Chitprapassorn
Chanprapaph, Kumutnart
Vachiramon, Vasanop
المصدر
Dermatology Research and Practice
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-10
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Acute generalized exanthematous pustulosis (AGEP) is an acute pustular eruption characterized by widespread nonfollicular sterile pustules.
The aim of this study is to characterize the etiology, clinical features, laboratory findings, management, and outcome of patients with AGEP in Asians.
Patient/Methods.
A retrospective analysis was performed on patient who presented with AGEP between August 2008 and November 2012 in a tertiary center in Thailand.
Results.
Nineteen patients with AGEP were included.
AGEP was generally distributed in seventeen patients (89.5%) and localized in two (10.5%).
Fever and neutrophilia occurred in 52.6% and 68.4%, respectively.
Hepatitis was found up to 26.3%.
The most common etiology was drugs (94.7%), comprising of antibiotics (73.6%), proton pump inhibitors (10.5%), nonsteroidal anti-inflammatory drugs (5.3%), and herbal medicine (5.3%).
Beta-lactams were the most common causal drug, particularly carbapenems and cephalosporins.
This is the first report of Andrographis paniculata as an offending agent for AGEP.
We found no differences between various treatment regimens (topical corticosteroid, systemic corticosteroid, and supportive treatment) regarding the time from drug cessation to pustules resolution ( P = 0.171 ).
Conclusions.
We have highlighted the presentation of AGEP among Asians.
We found high association with systemic drugs.
Carbapenems were one of the leading culprit drugs.
Finally, a localized variant was observed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Thienvibul, Chitprapassorn& Vachiramon, Vasanop& Chanprapaph, Kumutnart. 2015. Five-Year Retrospective Review of Acute Generalized Exanthematous Pustulosis. Dermatology Research and Practice،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1061099
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Thienvibul, Chitprapassorn…[et al.]. Five-Year Retrospective Review of Acute Generalized Exanthematous Pustulosis. Dermatology Research and Practice No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1061099
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Thienvibul, Chitprapassorn& Vachiramon, Vasanop& Chanprapaph, Kumutnart. Five-Year Retrospective Review of Acute Generalized Exanthematous Pustulosis. Dermatology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1061099
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1061099
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر