Antiviral Action of Hydromethanolic Extract of Geopropolis from Scaptotrigona postica against Antiherpes Simplex Virus (HSV-1)
المؤلفون المشاركون
Negri, G.
Coelho, Guilherme Rabelo
Mendonça, Ronaldo Zucatelli
Vilar, Karina de Senna
Figueiredo, Cristina Adelaide
Badari, Juliana Cuoco
Taniwaki, Noemi
Namiyama, Gisleine
Oliveira, Maria Isabel de
Curti, Suely Pires
Evelyn Silva, Patricia
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-11
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
The studies on chemical composition and biological activity of propolis had focused mainly on species Apis mellifera L.
(Hymenoptera: Apidae).
There are few studies about the uncommon propolis collected by stingless bees of the Meliponini tribe known as geopropolis.
The geopropolis from Scaptotrigona postica was collected in the region of Barra do Corda, Maranhão state, Brazil.
The chemical analysis of hydromethanolic extract of this geopropolis (HMG) was carried out through HPLC-DAD-ESI-MS/MS and the main constituents found were pyrrolizidine alkaloids and C-glycosyl flavones.
The presence of alkaloids in extracts of propolis is detected for the first time in this sample.
The antiviral activity of HMG was evaluated through viral DNA quantification experiments and electron microscopy experiments.
Quantification of viral DNA from herpes virus showed reduction of about 98% in all conditions and concentration tested of the HMG extract.
The results obtained were corroborated by transmission electron microscopy, in which the images did not show particle or viral replication complex.
The antiviral activity of C-glycosyl flavones was reported for a variety of viruses, being observed at different points in the viral replication.
This work is the first report about the antiviral activity of geopropolis from Scaptotrigona postica, in vitro, against antiherpes simplex virus (HSV).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Coelho, Guilherme Rabelo& Mendonça, Ronaldo Zucatelli& Vilar, Karina de Senna& Figueiredo, Cristina Adelaide& Badari, Juliana Cuoco& Taniwaki, Noemi…[et al.]. 2015. Antiviral Action of Hydromethanolic Extract of Geopropolis from Scaptotrigona postica against Antiherpes Simplex Virus (HSV-1). Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1061325
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Coelho, Guilherme Rabelo…[et al.]. Antiviral Action of Hydromethanolic Extract of Geopropolis from Scaptotrigona postica against Antiherpes Simplex Virus (HSV-1). Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1061325
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Coelho, Guilherme Rabelo& Mendonça, Ronaldo Zucatelli& Vilar, Karina de Senna& Figueiredo, Cristina Adelaide& Badari, Juliana Cuoco& Taniwaki, Noemi…[et al.]. Antiviral Action of Hydromethanolic Extract of Geopropolis from Scaptotrigona postica against Antiherpes Simplex Virus (HSV-1). Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1061325
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1061325
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر