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Comparisons of Ethanol Extracts of Chinese Propolis (Poplar Type) and Poplar Gums Based on the Antioxidant Activities and Molecular Mechanism
المؤلفون المشاركون
Zhang, Jianglin
Cao, Xueping
Ping, Shun
Wang, Kai
Shi, Jinhu
Zhang, Cuiping
Zheng, Huoqing
Hu, Fuliang
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-02-23
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
The biological activities of propolis are varied from plant sources and the prominent antioxidant effects of Chinese propolis (poplar type) have been extensively reported.
Oxidative stress is associated with inflammation and induces many diseases.
In the study, to evaluate antioxidant capacities and clarify the underlying molecular mechanisms of ethanol extracts of Chinese propolis (EECP) and ethanol extracts of poplar gums (EEPG), we analyzed their compositions by HPLC, evaluating their free radical scavenging activities and reducing power by chemical analysis methods.
Moreover, we studied the roles of EECP and EEPG on the elimination of ROS and expressions of antioxidant genes (HO-1, TrxR1, GCLM, and GCLC) in RAW264.7 cells.
We further investigated the effects of MAPKs on the antioxidant genes expression by specific inhibitors.
The nucleus translocation effects of Nrf2 were also measured by confocal microscopy analysis.
The results indicated that EECP had higher TPC and FDC values but regarding TFC values were not significant.
EECP also possessed more contents of 11 compounds than EEPG.
Both phytochemical analysis and cell experiment reflected that EECP exerted stronger antioxidant activities than EEPG.
EECP and EEPG enhanced endogenous antioxidant defenses by eliminating reactive oxygen species directly and activating Erk-Nrf2-HO1, GCLM, and TrxR1 signal pathways.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Jianglin& Cao, Xueping& Ping, Shun& Wang, Kai& Shi, Jinhu& Zhang, Cuiping…[et al.]. 2015. Comparisons of Ethanol Extracts of Chinese Propolis (Poplar Type) and Poplar Gums Based on the Antioxidant Activities and Molecular Mechanism. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-15.
https://search.emarefa.net/detail/BIM-1061336
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Jianglin…[et al.]. Comparisons of Ethanol Extracts of Chinese Propolis (Poplar Type) and Poplar Gums Based on the Antioxidant Activities and Molecular Mechanism. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-15.
https://search.emarefa.net/detail/BIM-1061336
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Jianglin& Cao, Xueping& Ping, Shun& Wang, Kai& Shi, Jinhu& Zhang, Cuiping…[et al.]. Comparisons of Ethanol Extracts of Chinese Propolis (Poplar Type) and Poplar Gums Based on the Antioxidant Activities and Molecular Mechanism. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-15.
https://search.emarefa.net/detail/BIM-1061336
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1061336
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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