An In Vitro System Comprising Immortalized Hypothalamic Neuronal Cells (GT1–7 Cells) for Evaluation of the Neuroendocrine Effects of Essential Oils
المؤلفون المشاركون
Mizuno, Dai
Konoha-Mizuno, Keiko
Mori, Miwako
Yamazaki, Kentaro
Haneda, Toshihiro
Koyama, Hironari
Kawahara, Masahiro
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-10-21
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Aromatherapy and plant-based essential oils are widely used as complementary and alternative therapies for symptoms including anxiety.
Furthermore, it was reportedly effective for the care of several diseases such as Alzheimer’s disease and depressive illness.
To investigate the pharmacological effects of essential oils, we developed an in vitro assay system using immortalized hypothalamic neuronal cells (GT1–7 cells).
In this study, we evaluated the effects of essential oils on neuronal death induced by hydrogen peroxide (H2O2), aluminum, zinc, or the antagonist of estrogen receptor (tamoxifen).
Among tests of various essential oils, we found that H2O2-induced neuronal death was attenuated by the essential oils of damask rose, eucalyptus, fennel, geranium, ginger, kabosu, mandarin, myrrh, and neroli.
Damask rose oil had protective effects against aluminum-induced neurotoxicity, while geranium and rosemary oil showed protective activity against zinc-induced neurotoxicity.
In contrast, geranium oil and ginger oil enhanced the neurotoxicity of tamoxifen.
Our in vitro assay system could be useful for the neuropharmacological and endocrine pharmacological studies of essential oils.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mizuno, Dai& Konoha-Mizuno, Keiko& Mori, Miwako& Yamazaki, Kentaro& Haneda, Toshihiro& Koyama, Hironari…[et al.]. 2015. An In Vitro System Comprising Immortalized Hypothalamic Neuronal Cells (GT1–7 Cells) for Evaluation of the Neuroendocrine Effects of Essential Oils. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1061370
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mizuno, Dai…[et al.]. An In Vitro System Comprising Immortalized Hypothalamic Neuronal Cells (GT1–7 Cells) for Evaluation of the Neuroendocrine Effects of Essential Oils. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1061370
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mizuno, Dai& Konoha-Mizuno, Keiko& Mori, Miwako& Yamazaki, Kentaro& Haneda, Toshihiro& Koyama, Hironari…[et al.]. An In Vitro System Comprising Immortalized Hypothalamic Neuronal Cells (GT1–7 Cells) for Evaluation of the Neuroendocrine Effects of Essential Oils. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1061370
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1061370
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر