Myelinated Afferents Are Involved in Pathology of the Spontaneous Electrical Activity and Mechanical Hyperalgesia of Myofascial Trigger Spots in Rats
المؤلفون المشاركون
Meng, Fei
Ge, Hong-You
Wang, Yong-Hui
Yue, Shou-Wei
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-05-10
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Myofascial trigger points (MTrPs) are common causes for chronic pain.
Myelinated afferents were considered to be related with muscular pain, and our clinical researches indicated they might participate in the pathology of MTrPs.
Here, we applied myofascial trigger spots (MTrSs, equal to MTrPs in human) of rats to further investigate role of myelinated afferents.
Modified pyridine-silver staining revealed more nerve endings at MTrSs than non-MTrSs (P<0.01), and immunohistochemistry with Neurofilament 200 indicated more myelinated afferents existed in MTrSs (P<0.01).
Spontaneous electrical activity (SEA) recordings at MTrSs showed that specific block of myelinated afferents in sciatic nerve with tetrodotoxin (TTX) led to significantly decreased SEA (P<0.05).
Behavioral assessment showed that mechanical pain thresholds (MPTs) of MTrSs were lower than those of non-MTrSs (P<0.01).
Block of myelinated afferents by intramuscular TTX injection increased MPTs of MTrSs significantly (P<0.01), while MPTs of non-MTrSs first decreased (P<0.05) and then increased (P>0.05).
30 min after the injection, MPTs at MTrSs were significantly lower than those of non-MTrSs (P<0.01).
Therefore, we concluded that proliferated myelinated afferents existed at MTrSs, which were closely related to pathology of SEA and mechanical hyperalgesia of MTrSs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Meng, Fei& Ge, Hong-You& Wang, Yong-Hui& Yue, Shou-Wei. 2015. Myelinated Afferents Are Involved in Pathology of the Spontaneous Electrical Activity and Mechanical Hyperalgesia of Myofascial Trigger Spots in Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1061466
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Meng, Fei…[et al.]. Myelinated Afferents Are Involved in Pathology of the Spontaneous Electrical Activity and Mechanical Hyperalgesia of Myofascial Trigger Spots in Rats. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1061466
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Meng, Fei& Ge, Hong-You& Wang, Yong-Hui& Yue, Shou-Wei. Myelinated Afferents Are Involved in Pathology of the Spontaneous Electrical Activity and Mechanical Hyperalgesia of Myofascial Trigger Spots in Rats. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1061466
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1061466
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر