Herb Network Analysis for a Famous TCM Doctor's Prescriptions on Treatment of Rheumatoid Arthritis
المؤلفون المشاركون
Li, Yan
Li, Rui
Ouyang, Zibo
Li, Shao
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-04-23
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Traditional Chinese Medicine (TCM) doctors always prescribe various herbal formulae tailored to individual patients.
However, there is still a lack of appropriate methods to study the rule and potential biological basis underlying the numerous prescriptions.
Here we developed an Herb-Compound-Target-Disease coherent network approach to analyze 871 herbal prescriptions from a TCM master, Mr.
Ji-Ren Li, in his clinical practice on treatment of rheumatoid arthritis (RA).
The core herb networks were extracted from Mr.
Li’s prescriptions.
Then, we predicted target profiles of compounds in core herb networks and calculated potential synergistic activities among them.
We further found that the target sets of core herbs overlapped significantly with the RA related biological processes and pathways.
Moreover, we detected a possible connection between the prescribed herbs with different properties such as Cold and Hot and the Western drugs with different actions such as immunomodulatory and hormone regulation on treatment of RA.
In summary, we explored a new application of TCM network pharmacology on the analysis of TCM prescriptions and detected the networked core herbs, their potential synergistic and biological activities, and possible connections with drugs.
This work offers a novel way to understand TCM prescriptions in clinical practice.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Yan& Li, Rui& Ouyang, Zibo& Li, Shao. 2015. Herb Network Analysis for a Famous TCM Doctor's Prescriptions on Treatment of Rheumatoid Arthritis. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1061509
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Yan…[et al.]. Herb Network Analysis for a Famous TCM Doctor's Prescriptions on Treatment of Rheumatoid Arthritis. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1061509
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Yan& Li, Rui& Ouyang, Zibo& Li, Shao. Herb Network Analysis for a Famous TCM Doctor's Prescriptions on Treatment of Rheumatoid Arthritis. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1061509
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1061509
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر