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Preliminary Studies of the Immunomodulator Effect of the Bougainvillea xbuttiana Extract in a Mouse Model
المؤلفون المشاركون
Barbosa Navarro, L.
Arteaga Figueroa, Lluvia
Patiño Vera, Martin
Petricevich, Vera L.
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-16
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Bougainvillea xbuttiana is used as an analgesic in folk medicine in Mexico.
The purpose of the present study was to determine the effects of the ethanolic extract from B.
xbuttiana on macrophages activities.
The phytochemical screening was performed for determine the presence of alkaloids, flavonoids, triterpenes, and saponins.
The effects of B.
xbuttiana were analyzed using the macrophages activities as determined by the H2O2 release, spreading and phagocytic index, vacuoles formation percentage, and mediators production.
The viability percentage was determined in live cells after fixing and staining with crystal violet.
The presence of H2O2 in macrophages was performed by using the peroxidase-phenol red solution.
The cytokine production was determined by two assays, ELISA for detection of IL-6, IL-10, and IFN-γ and biological assay for TNF detection.
The results showed that the Bxb extract dose-dependent manner produces (a) an increase in levels of H2O2 and spreading and vacuoles formation percentages, (b) a decrease in phagocytic index and in the amounts of TNF, IL-6, and IFN-γ, and (c) an increase significant in IL-10 and NO production.
This study indicates that the ethanolic extract from Bougainvillea xbuttiana was able to activate macrophages.
The combination of these results suggests that this extract has an immunomodulator effect.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Arteaga Figueroa, Lluvia& Barbosa Navarro, L.& Patiño Vera, Martin& Petricevich, Vera L.. 2015. Preliminary Studies of the Immunomodulator Effect of the Bougainvillea xbuttiana Extract in a Mouse Model. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1061550
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Arteaga Figueroa, Lluvia…[et al.]. Preliminary Studies of the Immunomodulator Effect of the Bougainvillea xbuttiana Extract in a Mouse Model. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1061550
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Arteaga Figueroa, Lluvia& Barbosa Navarro, L.& Patiño Vera, Martin& Petricevich, Vera L.. Preliminary Studies of the Immunomodulator Effect of the Bougainvillea xbuttiana Extract in a Mouse Model. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1061550
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1061550
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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