Ozone Therapy in the Management of Persistent Radiation-Induced Rectal Bleeding in Prostate Cancer Patients
المؤلفون المشاركون
Clavo, Bernardino
Santana-Rodriguez, Norberto
Llontop, Pedro
Gutierrez, Dominga
Ceballos, Daniel
Méndez, Charlin
Rovira, Gloria
Suarez, Gerardo
Rey-Baltar, Dolores
Garcia-Cabrera, Laura
Fiuza, Dolores
Martínez-Sánchez, Gregorio
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-08-18
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Introduction.
Persistent radiation-induced proctitis and rectal bleeding are debilitating complications with limited therapeutic options.
We present our experience with ozone therapy in the management of such refractory rectal bleeding.
Methods.
Patients (n=12) previously irradiated for prostate cancer with persistent or severe rectal bleeding without response to conventional treatment were enrolled to receive ozone therapy via rectal insufflations and/or topical application of ozonized-oil.
Ten (83%) patients had Grade 3 or Grade 4 toxicity.
Median follow-up after ozone therapy was 104 months (range: 52–119).
Results.
Following ozone therapy, the median grade of toxicity improved from 3 to 1 (p<0.001) and the number of endoscopy treatments from 37 to 4 (p=0.032).
Hemoglobin levels changed from 11.1 (7–14) g/dL to 13 (10–15) g/dL, before and after ozone therapy, respectively (p=0.008).
Ozone therapy was well tolerated and no adverse effects were noted, except soft and temporary flatulence for some hours after each session.
Conclusions.
Ozone therapy was effective in radiation-induced rectal bleeding in prostate cancer patients without serious adverse events.
It proved useful in the management of rectal bleeding and merits further evaluation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Clavo, Bernardino& Santana-Rodriguez, Norberto& Llontop, Pedro& Gutierrez, Dominga& Ceballos, Daniel& Méndez, Charlin…[et al.]. 2015. Ozone Therapy in the Management of Persistent Radiation-Induced Rectal Bleeding in Prostate Cancer Patients. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1061552
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Clavo, Bernardino…[et al.]. Ozone Therapy in the Management of Persistent Radiation-Induced Rectal Bleeding in Prostate Cancer Patients. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1061552
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Clavo, Bernardino& Santana-Rodriguez, Norberto& Llontop, Pedro& Gutierrez, Dominga& Ceballos, Daniel& Méndez, Charlin…[et al.]. Ozone Therapy in the Management of Persistent Radiation-Induced Rectal Bleeding in Prostate Cancer Patients. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1061552
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1061552
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر