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The effect of immunosuppressive agents on lipid profile of post renal transplant patients
المؤلفون المشاركون
al-Nusur, Wafa Mahmud
Ghanimat, Muhammad
al-Abbadi, Rabiah
المصدر
Journal of the Royal Medical Services
العدد
المجلد 13، العدد 2 (30 ديسمبر/كانون الأول 2006)4ص.
الناشر
الخدمات الطبية الملكية الأردنية
تاريخ النشر
2006-12-30
دولة النشر
الأردن
عدد الصفحات
4
التخصصات الرئيسية
الموضوعات
الملخص EN
Objective: To determine the effect of the different immunosuppressive medications on the lipid profile of renal transplant recipients with normal renal functions. Methods: A Single blinded study was conducted on patients who underwent live-related renal transplants at Queen Alia Military Hospital between January 2001 and March 2003. They were divided into two groups according to the immunosuppressive treatment.
Group I: On tacrolimus and Group II: On ciclosporine (Neoral)®.
Both groups received in addition steroids and either azathioprine or Mycophenolate Mofitel. Inclusion Criteria includes normal blood glucose and normal lipid profile prior to transplantation. Total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides were measured monthly for at least three months after transplantation. Statistical significance was considered if P <_0.05. Results: In both groups, the mean total cholesterol, low-density lipoprotein cholesterol and triglycerides were indifferent; while there was a statistically significant difference between the two groups in high-density lipoprotein cholesterol in favor of the ciclosporine (Neoral) group. Conclusion: Tacrolimus and ciclosporine have a similar effect on total cholesterol, low-density lipoprotein cholesterol and triglycerides; while Ciclosporine is better in raising the high-density lipoprotein cholesterol.
Further long-term studies are required to determine the effect of these lipid profile changes on cardiovascular morbidity and mortality.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ghanimat, Muhammad& al-Nusur, Wafa Mahmud& al-Abbadi, Rabiah. 2006. The effect of immunosuppressive agents on lipid profile of post renal transplant patients. Journal of the Royal Medical Services،Vol. 13, no. 2.
https://search.emarefa.net/detail/BIM-106281
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ghanimat, Muhammad…[et al.]. The effect of immunosuppressive agents on lipid profile of post renal transplant patients. Journal of the Royal Medical Services Vol. 13, no. 2 (Dec. 2006).
https://search.emarefa.net/detail/BIM-106281
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ghanimat, Muhammad& al-Nusur, Wafa Mahmud& al-Abbadi, Rabiah. The effect of immunosuppressive agents on lipid profile of post renal transplant patients. Journal of the Royal Medical Services. 2006. Vol. 13, no. 2.
https://search.emarefa.net/detail/BIM-106281
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-106281
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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