An Herbal Galactagogue Mixture Increases Milk Production and Aquaporin Protein Expression in the Mammary Glands of Lactating Rats
المؤلفون المشاركون
Liu, Haibin
Hua, Ying
Luo, Hui
Shen, Zhaojun
Tao, Xuejiao
Zhu, Xueqiong
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-05-05
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Herbal galactagogues have been increasingly used to treat postpartum hypogalactia.
The mechanism of action of herbal galactagogues remains unclear.
The purpose of this study was to investigate the effect of an herbal galactagogue mixture on milk production and aquaporin (AQP) expression in lactating rats.
Methods.
Thirty female Sprague Dawley rats were randomized into virgin, lactating + H2O, and lactating + galactagogue groups (n=10 per group).
Lactating rats were administered the decoction of an herbal galactagogue mixture by oral gavage or the same amount of distilled water.
Results.
The herbal decoction significantly increased milk production in lactating rats (P<0.05).
Both immunohistochemical staining and western blot showed that protein levels of AQP-3 and AQP-5 were significantly increased during lactation compared with virgin stage and the herbal decoction further elevated their expression (P<0.05).
AQP-1 was predominantly expressed in the capillaries whereas AQP-3 and AQP-5 were mainly detected in the epithelial cells and ducts of the mammary glands.
Conclusion.
The expression of AQPs in the mammary glands of rats was developmentally regulated.
Herbal galactagogues might have increased milk secretion by regulating the expression and function of AQPs in the mammary glands.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Haibin& Hua, Ying& Luo, Hui& Shen, Zhaojun& Tao, Xuejiao& Zhu, Xueqiong. 2015. An Herbal Galactagogue Mixture Increases Milk Production and Aquaporin Protein Expression in the Mammary Glands of Lactating Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1063571
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Haibin…[et al.]. An Herbal Galactagogue Mixture Increases Milk Production and Aquaporin Protein Expression in the Mammary Glands of Lactating Rats. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1063571
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Haibin& Hua, Ying& Luo, Hui& Shen, Zhaojun& Tao, Xuejiao& Zhu, Xueqiong. An Herbal Galactagogue Mixture Increases Milk Production and Aquaporin Protein Expression in the Mammary Glands of Lactating Rats. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1063571
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1063571
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر