Apple Peel Supplemented Diet Reduces Parameters of Metabolic Syndrome and Atherogenic Progression in ApoE−− Mice

المؤلفون المشاركون

Donoso, W.
Gonzalez, Jaime
Morales, Erik
Sandoval, Nathalie
Reyes, María
Gonzalez, Priscila
Gajardo, Monica
Neira, Amalia
Razmilic, Iván
Yuri, José A.
Moore-Carrasco, Rodrigo

المصدر

Evidence-Based Complementary and Alternative Medicine

العدد

المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2015-05-17

دولة النشر

مصر

عدد الصفحات

10

التخصصات الرئيسية

الطب البشري

الملخص EN

Cardiovascular Diseases (CVD) represent about 30% of all causes of death worldwide.

The development of CVD is related in many cases with the previous existence of metabolic syndrome (MS).

It is known that apple consumption has a cardiovascular protecting effect, containing phenolic compounds with antioxidant effect, which are concentrated in the fruit peel.

The objective of this study was to test the effect of apple peel consumption in a murine model of MS and apoE−/− mice.

Apple supplemented diets reduced the biochemical parameters (glycaemia, total cholesterol, HDL-cholesterol, LDL-cholesterol, ureic nitrogen, triglycerides, insulin, and asymmetric dimethylarginine (ADMA)) of MS model in CF1 mice significantly.

The model apoE−/− mouse was used to evaluate the capacity of the apple peel to revert the progression of the atherogenesis.

FD with HAP reverts cholesterol significantly and slows down the progression of the plate diminishing the cholesterol accumulation area.

With these results, it can be concluded that the consumption of apple peel reduces several MS parameters and the atherogenic progression in mice.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Gonzalez, Jaime& Donoso, W.& Sandoval, Nathalie& Reyes, María& Gonzalez, Priscila& Gajardo, Monica…[et al.]. 2015. Apple Peel Supplemented Diet Reduces Parameters of Metabolic Syndrome and Atherogenic Progression in ApoE−− Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1063797

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Gonzalez, Jaime…[et al.]. Apple Peel Supplemented Diet Reduces Parameters of Metabolic Syndrome and Atherogenic Progression in ApoE−− Mice. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1063797

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Gonzalez, Jaime& Donoso, W.& Sandoval, Nathalie& Reyes, María& Gonzalez, Priscila& Gajardo, Monica…[et al.]. Apple Peel Supplemented Diet Reduces Parameters of Metabolic Syndrome and Atherogenic Progression in ApoE−− Mice. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1063797

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1063797