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Ginger and Its Constituents: Role in Prevention and Treatment of Gastrointestinal Cancer
المؤلفون المشاركون
Prasad, Sahdeo
Kumar Tyagi, Amit
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-08
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Gastrointestinal (GI) cancer, a cancer of different organs of the digestive system, is one of the most common cancers around the world.
The incidence and death rate of some of these cancers are very high.
Although a large variety of chemotherapeutic agents have been introduced since the last few decades to combat GI cancer, most of them are very expensive and have side effects.
Therefore, the compounds derived from natural sources, which are considered to be safe and cost effective, are needed.
Ginger (Zingiber officinale) is one of the most widely used natural products consumed as a spice and medicine for treating nausea, dysentery, heartburn, flatulence, diarrhea, loss of appetite, infections, cough, and bronchitis.
Experimental studies showed that ginger and its active components including 6-gingerol and 6-shogaol exert anticancer activities against GI cancer.
The anticancer activity of ginger is attributed to its ability to modulate several signaling molecules like NF-κB, STAT3, MAPK, PI3K, ERK1/2, Akt, TNF-α, COX-2, cyclin D1, cdk, MMP-9, survivin, cIAP-1, XIAP, Bcl-2, caspases, and other cell growth regulatory proteins.
In this review, the evidences for the chemopreventive and chemotherapeutic potential of ginger extract and its active components using in vitro, animal models, and patients have been described.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Prasad, Sahdeo& Kumar Tyagi, Amit. 2015. Ginger and Its Constituents: Role in Prevention and Treatment of Gastrointestinal Cancer. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1063921
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Prasad, Sahdeo& Kumar Tyagi, Amit. Ginger and Its Constituents: Role in Prevention and Treatment of Gastrointestinal Cancer. Gastroenterology Research and Practice No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1063921
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Prasad, Sahdeo& Kumar Tyagi, Amit. Ginger and Its Constituents: Role in Prevention and Treatment of Gastrointestinal Cancer. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1063921
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1063921
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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