Optimization of Deep Sedation with Spontaneous Respiration for Therapeutic Endoscopy Combining Propofol and Bispectral Index Monitoring
المؤلفون المشاركون
Asaoka, Daisuke
Matsumoto, Kohei
Akazawa, Yoichi
Komori, Hiroyuki
Nakagawa, Yuta
Takeda, Tsutomu
Shimada, Yuji
Ueyama, Hiroya
Hojo, Mariko
Nagahara, Akihito
Matsumoto, Kenshi
Watanabe, Sumio
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-08-13
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background/Aims.
This study aimed to establish optimal propofol anesthesia for therapeutic endoscopy, which has not been established.
Methodology.
We retrospectively investigated data on 89 patients who underwent upper-GI endoscopic submucosal dissection or endoscopic mucosal resection under anesthesia with propofol.
Examined doses of propofol were changed according to efficacy and/or adverse events and classified into 5 periods.
A bispectral index (BIS) monitor was used at Period 5 to decrease the incidence of adverse events caused by oversedation.
The initial dose of propofol was administered after bolus injection of pethidine hydrochloride (0.5 mg/kg), and 1.0 mL of propofol was added every minute until the patients fell asleep.
Continuous and bolus infusion were performed to maintain sedation.
When the patient moved or an adverse event occurred, the maintenance dose examined was increased or decreased by 5 mL/h regardless of body weight.
Results.
Dose combinations (introduction : maintenance) and patient numbers for each period were as follows: Period 1 ( n = 27 ), 0.5 mg/kg : 5 mg/kg/h; Period 2 ( n = 11 ), 0.33 mg/kg : 3.3 mg/kg/h; Period 3 ( n = 7 ), 0.5 mg/kg : 3.3 mg/kg/h; Period 4 ( n = 14 ), 0.5 mg/kg : 2.5 mg/kg/h; Period 5 ( n = 30 ), 0.5 mg/kg : 2.5 mg/kg/h, using BIS monitor.
During Period 5, an adverse event occurred in 10.0% of patients, which was lower than that for Periods 1–4.
Conclusions.
Period 5 propofol anesthesia with BIS protocol could be safe and useful for therapeutic endoscopy under deep sedation with spontaneous respiration.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Matsumoto, Kohei& Nagahara, Akihito& Matsumoto, Kenshi& Akazawa, Yoichi& Komori, Hiroyuki& Nakagawa, Yuta…[et al.]. 2015. Optimization of Deep Sedation with Spontaneous Respiration for Therapeutic Endoscopy Combining Propofol and Bispectral Index Monitoring. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1063949
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Matsumoto, Kohei…[et al.]. Optimization of Deep Sedation with Spontaneous Respiration for Therapeutic Endoscopy Combining Propofol and Bispectral Index Monitoring. Gastroenterology Research and Practice No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1063949
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Matsumoto, Kohei& Nagahara, Akihito& Matsumoto, Kenshi& Akazawa, Yoichi& Komori, Hiroyuki& Nakagawa, Yuta…[et al.]. Optimization of Deep Sedation with Spontaneous Respiration for Therapeutic Endoscopy Combining Propofol and Bispectral Index Monitoring. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1063949
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1063949
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر