Rescue Therapy with a Proton Pump Inhibitor Plus Amoxicillin and Rifabutin for Helicobacter pylori Infection: A Systematic Review and Meta-Analysis
المؤلفون المشاركون
Lv, Nonghua
Zhou, Xiaojiang
Liu, Xiaoqun
Wang, Hui
Lv, Zhifa
Wang, Youhua
Wang, Ben
Xie, Yong
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-05-25
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Background.
To conduct a systematic review and meta-analysis of clinical trials for eradication of Helicobacter pylori (H.
pylori) that included a treatment arm with a proton pump inhibitor, rifabutin, and amoxicillin.
Materials and Methods.
We selected clinical trials that examined the efficacy of H.
pylori eradication therapies and included a study arm using the test regimen from major medical literature databases and abstracts from major gastroenterology meetings.
We also did subgroup and sensitivity analyses.
Results.
Twenty-one studies were included in systematic review.
The total eradication rates of the test regimen were 70.4% by intent-to-treat (ITT) and 72.0% by per-protocol (PP) analyses.
The pooled odds ratio (OR) was 0.55 using fixed effects model (P=0.283) for the test regimen versus other triple regimens.
The total eradication rates were 68.4% for the test regimen and 81.9% in the control group by ITT, while the OR was 1.08 using random effects model (P=0.019).
The pooled eradication rate was 66.4% for the test regimen and 67.4% for the control group by ITT.
The total adverse effects incidence were 25.1% for the test regimen.
Conclusions.
The test regimen for H.
pylori rescue therapy may be not superior to control regimens in efficacy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Xiaoqun& Wang, Hui& Lv, Zhifa& Wang, Youhua& Wang, Ben& Xie, Yong…[et al.]. 2015. Rescue Therapy with a Proton Pump Inhibitor Plus Amoxicillin and Rifabutin for Helicobacter pylori Infection: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1063975
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Xiaoqun…[et al.]. Rescue Therapy with a Proton Pump Inhibitor Plus Amoxicillin and Rifabutin for Helicobacter pylori Infection: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1063975
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Xiaoqun& Wang, Hui& Lv, Zhifa& Wang, Youhua& Wang, Ben& Xie, Yong…[et al.]. Rescue Therapy with a Proton Pump Inhibitor Plus Amoxicillin and Rifabutin for Helicobacter pylori Infection: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1063975
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1063975
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر