Analysis of the Serum Bile Acid Composition for Differential Diagnosis in Patients with Liver Disease
المؤلفون المشاركون
Amano, Katsushi
Nakano, Masanori
Masubuchi, Noriko
Sugihara, Masahiro
Matsuura, Tomokazu
Sugita, Tomonori
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-03
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Objectives.
We determined the serum bile acid (BA) composition in patients with liver diseases and healthy volunteers to investigate the relationship between the etiologies of liver disease and BA metabolism.
Material and Methods.
Sera from 150 patients with liver diseases and 46 healthy volunteers were obtained.
The serum concentrations of the 16 different BAs were determined according to the LC-MS/MS method and were compared between the different liver diseases.
Results.
A total of 150 subjects, including patients with hepatitis C virus (HCV) ( n = 44 ), hepatitis B virus (HBV) ( n = 23 ), alcoholic liver disease (ALD) ( n = 21 ), biliary tract disease ( n = 20 ), nonalcoholic fatty liver disease (NAFLD) ( n = 13 ), and other liver diseases ( n = 29 ), were recruited.
The levels of UDCA and GUDCA were significantly higher in the ALD group, and the levels of DCA and UDCA were significantly lower in the biliary tract diseases group than in viral hepatitis group.
In the UDCA therapy (−) subgroup, a significantly lower level of TLCA was observed in the ALD group, with lower levels of CDCA, DCA, and GLCA noted in biliary tract diseases group compared to viral hepatitis group.
Conclusions.
Analysis of the BA composition may be useful for differential diagnosis in liver disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sugita, Tomonori& Amano, Katsushi& Nakano, Masanori& Masubuchi, Noriko& Sugihara, Masahiro& Matsuura, Tomokazu. 2015. Analysis of the Serum Bile Acid Composition for Differential Diagnosis in Patients with Liver Disease. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1064103
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sugita, Tomonori…[et al.]. Analysis of the Serum Bile Acid Composition for Differential Diagnosis in Patients with Liver Disease. Gastroenterology Research and Practice No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1064103
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sugita, Tomonori& Amano, Katsushi& Nakano, Masanori& Masubuchi, Noriko& Sugihara, Masahiro& Matsuura, Tomokazu. Analysis of the Serum Bile Acid Composition for Differential Diagnosis in Patients with Liver Disease. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1064103
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1064103
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر