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C-Reactive Protein and Breast Cancer: New Insights from Old Molecule
المؤلفون المشاركون
Asegaonkar, Shilpa Balaji
Asegaonkar, Balaji Narayanrao
Takalkar, Unmesh Vidyadhar
Advani, Suresh
Thorat, Anand Pandurang
المصدر
International Journal of Breast Cancer
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-11-26
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Recently an association between breast cancer and inflammation has emerged as the seventh hallmark of cancer.
Chronic inflammation is a key contributor in the development and progression of carcinogenesis.
Inflammatory pathways play an important role in the causation of breast cancer.
C-reactive protein (CRP) an acute-phase reactant inflammatory protein is synthesized in hepatocytes in response to cytokines that are released from leucocytes within the tumor microenvironment.
Several epidemiological studies appraised an association of CRP with breast cancer risk with inconsistent findings.
Elevated levels at the time of diagnosis of breast cancer indicate aggressiveness of the tumor.
CRP is also a well-established independent prognostic marker.
Breast cancer survivors with the state of chronic inflammation are at risk of recurrence and metabolic disturbances.
CRP lowering agents along with chemotherapeutic drugs will improve the survival of breast cancer patients.
Also, it is a risk predictor for subsequent cardiotoxicity in patients receiving chemotherapy.
The present review is aimed at elucidating the role of C-reactive protein, as an inflammatory risk marker and prognostic predictor of breast cancer.
It also focuses on conflicting views on the role of CRP in breast cancer and its impact on therapeutic interventions.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Asegaonkar, Shilpa Balaji& Asegaonkar, Balaji Narayanrao& Takalkar, Unmesh Vidyadhar& Advani, Suresh& Thorat, Anand Pandurang. 2015. C-Reactive Protein and Breast Cancer: New Insights from Old Molecule. International Journal of Breast Cancer،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1065255
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Asegaonkar, Shilpa Balaji…[et al.]. C-Reactive Protein and Breast Cancer: New Insights from Old Molecule. International Journal of Breast Cancer No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1065255
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Asegaonkar, Shilpa Balaji& Asegaonkar, Balaji Narayanrao& Takalkar, Unmesh Vidyadhar& Advani, Suresh& Thorat, Anand Pandurang. C-Reactive Protein and Breast Cancer: New Insights from Old Molecule. International Journal of Breast Cancer. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1065255
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1065255
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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