Locoregional Recurrence Risk in Breast Cancer Patients with Estrogen Receptor Positive Tumors and Residual Nodal Disease following Neoadjuvant Chemotherapy and Mastectomy without Radiation Therapy
المؤلفون المشاركون
Kandula, Shravan
Harari, Saul
Fasola, Carolina
Mister, Donna
Yu, David S.
Zelnak, Amelia B.
Torres, Mylin A.
Switchenko, Jeffrey
المصدر
International Journal of Breast Cancer
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-07-21
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Among breast cancer patients treated with neoadjuvant chemotherapy (NAC) and mastectomy, locoregional recurrence (LRR) rates are unclear in women with ER+ tumors treated with adjuvant endocrine therapy without postmastectomy radiation (PMRT).
To determine if PMRT is needed in these patients, we compared LRR rates of patients with ER+ tumors (treated with adjuvant endocrine therapy) with women who have non-ER+ tumors.
85 consecutive breast cancer patients (87 breast tumors) treated with NAC and mastectomy without PMRT were reviewed.
Patients were divided by residual nodal disease (ypN) status (ypN+ versus ypN0) and then stratified by receptor subtype.
Among ypN+ patients ( n = 35 ), five-year LRR risk in patients with ER+, Her2+, and triple negative tumors was 5%, 33%, and 37%, respectively ( p = 0.02 ).
Among ypN+/ER+ patients, lymphovascular invasion and grade three disease increased the five-year LRR risk to 13% and 11%, respectively.
Among ypN0 patients ( n = 52 ), five-year LRR risk in patients with ER+, Her2+, and triple negative tumors was 7%, 22%, and 6%, respectively ( p = 0.71 ).
In women with ER+ tumors and residual nodal disease, endocrine therapy may be sufficient adjuvant treatment, except in patients with lymphovascular invasion or grade three tumors where PMRT may still be indicated.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kandula, Shravan& Switchenko, Jeffrey& Harari, Saul& Fasola, Carolina& Mister, Donna& Yu, David S.…[et al.]. 2015. Locoregional Recurrence Risk in Breast Cancer Patients with Estrogen Receptor Positive Tumors and Residual Nodal Disease following Neoadjuvant Chemotherapy and Mastectomy without Radiation Therapy. International Journal of Breast Cancer،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1065256
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kandula, Shravan…[et al.]. Locoregional Recurrence Risk in Breast Cancer Patients with Estrogen Receptor Positive Tumors and Residual Nodal Disease following Neoadjuvant Chemotherapy and Mastectomy without Radiation Therapy. International Journal of Breast Cancer No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1065256
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kandula, Shravan& Switchenko, Jeffrey& Harari, Saul& Fasola, Carolina& Mister, Donna& Yu, David S.…[et al.]. Locoregional Recurrence Risk in Breast Cancer Patients with Estrogen Receptor Positive Tumors and Residual Nodal Disease following Neoadjuvant Chemotherapy and Mastectomy without Radiation Therapy. International Journal of Breast Cancer. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1065256
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1065256
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر