Switching from Twice-Daily Basal Insulin Injections to Once-Daily Insulin Degludec Injection for Basal-Bolus Insulin Regimen in Japanese Patients with Type 1 Diabetes: A Pilot Study
المؤلفون المشاركون
Watada, Hirotaka
Uchida, Toyoyoshi
Fujitani, Yoshio
Tosaka, Yuka
Kanazawa, Akio
Ikeda, Fuki
Iida, Mayu
Sato, Junko
Matsumoto, Kazuhisa
Tamura, Yoshifumi
Ogihara, Takeshi
Mita, Tomoya
Shimizu, Tomoaki
Goto, Hiromasa
Ohmura, Chie
المصدر
International Journal of Endocrinology
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-09-07
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
The aim of this study was to investigate the efficacy of insulin degludec used for basal-bolus insulin regimen after switching from twice-daily basal insulin in Japanese patients with type 1 diabetes mellitus.
The subjects were 22 type 1 diabetes patients treated with basal-bolus insulin regimen with twice-daily basal insulin.
Basal insulin was switched to once-daily injection of insulin degludec with 10% dose reduction.
HbA1c and fasting plasma glucose (FPG) were measured before and 12 weeks after switching.
The frequency of hypoglycemic episodes, standard deviation (SD) of blood glucose, and mean of daily difference (MODD) were evaluated by continuous glucose monitoring (CGM) before and 4 weeks after switching.
HbA1c and FPG before and 12 weeks after switching were comparable (HbA1c 8.5 ± 1.4 versus 8.7 ± 1.6%, P = 0.28 ; FPG 203.2 ± 81.2 versus 206.5 ± 122.4 mg/dL, P = 0.91 ).
The frequency of hypoglycemia during nighttime was not significantly different at 4 weeks after switching (14.4 ± 17.0 versus 11.1 ± 15.0%, P = 0.45 ).
In addition, SD and MODD before and 4 weeks after switching were also comparable.
In conclusion, glycemic control under once-daily insulin degludec injection was almost comparable to that under twice-daily basal insulin injections in Japanese type 1 diabetes patients.
This study was registered with ID: UMIN000010474.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tosaka, Yuka& Kanazawa, Akio& Ikeda, Fuki& Iida, Mayu& Sato, Junko& Matsumoto, Kazuhisa…[et al.]. 2015. Switching from Twice-Daily Basal Insulin Injections to Once-Daily Insulin Degludec Injection for Basal-Bolus Insulin Regimen in Japanese Patients with Type 1 Diabetes: A Pilot Study. International Journal of Endocrinology،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1065582
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tosaka, Yuka…[et al.]. Switching from Twice-Daily Basal Insulin Injections to Once-Daily Insulin Degludec Injection for Basal-Bolus Insulin Regimen in Japanese Patients with Type 1 Diabetes: A Pilot Study. International Journal of Endocrinology No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1065582
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tosaka, Yuka& Kanazawa, Akio& Ikeda, Fuki& Iida, Mayu& Sato, Junko& Matsumoto, Kazuhisa…[et al.]. Switching from Twice-Daily Basal Insulin Injections to Once-Daily Insulin Degludec Injection for Basal-Bolus Insulin Regimen in Japanese Patients with Type 1 Diabetes: A Pilot Study. International Journal of Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1065582
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1065582
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر