Evaluating the Efficacy of Treatment with a GnRH Analogue in Patients with Central Precocious Puberty
المؤلفون المشاركون
Kendirci, H. Nur Peltek
Ağladıoğlu, Sebahat Yılmaz
Baş, Veysel N.
Önder, Aşan
Çetinkaya, Semra
Aycan, Zehra
المصدر
International Journal of Endocrinology
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-10-13
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
GnRH analogues (GnRHa) are used in the treatment of central precocious puberty (CPP).
The purpose of this study was to evaluate the efficacy of treatment with a GnRHa (leuprolide acetate) in patients with CPP.
Subjects and Methods.
A total of 62 female child patients who had been diagnosed with CPP, rapidly progressive precocious puberty (RP-PP), or advanced puberty (AP) and started on GnRHa treatment (leuprolide acetate, Lucrin depot, 3.75 mg once every 28 days) were included in the study.
The efficacy of treatment was evaluated with anthropometric data obtained, progression of pubertal symptoms observed, as well as GnRHa tests, and, when necessary, intravenous GnRH tests carried out in physical examinations that were performed once every 3 months.
Results.
In the current study, treatment of early/advanced puberty at a dose of 3.75 mg once every 28 days resulted in the suppression of the HHG axis in 85.5% of the patients.
Conclusion.
The findings of this study revealed that a high starting dose of leuprolide acetate may not be necessary in every patient for the treatment of CPP.
Starting at a dose of 3.75 mg once every 28 days and increasing it with regard to findings in follow-ups would be a better approach.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kendirci, H. Nur Peltek& Ağladıoğlu, Sebahat Yılmaz& Baş, Veysel N.& Önder, Aşan& Çetinkaya, Semra& Aycan, Zehra. 2015. Evaluating the Efficacy of Treatment with a GnRH Analogue in Patients with Central Precocious Puberty. International Journal of Endocrinology،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1065603
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kendirci, H. Nur Peltek…[et al.]. Evaluating the Efficacy of Treatment with a GnRH Analogue in Patients with Central Precocious Puberty. International Journal of Endocrinology No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1065603
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kendirci, H. Nur Peltek& Ağladıoğlu, Sebahat Yılmaz& Baş, Veysel N.& Önder, Aşan& Çetinkaya, Semra& Aycan, Zehra. Evaluating the Efficacy of Treatment with a GnRH Analogue in Patients with Central Precocious Puberty. International Journal of Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1065603
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1065603
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر