Isolated Subclinical Hyperthyrotropinemia in Obese Children: Does Levothyroxine (LT4)‎ Improve Weight Reduction during Combined Behavioral Therapy?

المؤلفون المشاركون

Matusik, Pawel
Malecka-Tendera, Ewa
Gawlik, Aneta
Januszek-Trzciakowska, Aleksandra

المصدر

International Journal of Endocrinology

العدد

المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2015-07-02

دولة النشر

مصر

عدد الصفحات

7

التخصصات الرئيسية

الأحياء

الملخص EN

Objective.

The study aim was to analyze whether anthropometrical parameters and TSH values in obese children with isolated subclinical hypothyroidism (IsHT) treated with levothyroxine (LT4) and weight reduction program differ from those managed by dietary and behavior counselling only.

Material and Methods.

51 obese children with IsHT, who were treated according to the same weight reduction program, were retrospectively analyzed.

They were divided into two groups: Group 1, n=26, and Group 2, n=25, without or with LT4 therapy, respectively.

Changes in anthropometrical (delta BMI z-score) and hormonal (delta TSH) status were analyzed at the first follow-up visit.

Results.

In both groups significant decrease of TSH and BMI z-score values were noted.

TSH normalized in 80.9% of children from Group 1 versus 90.5% from Group 2, p = NS.

Delta BMI z-score was insignificantly higher in Group 1 compared to Group 2.

Delta TSH was significantly related to initial TSH level in children treated by lifestyle intervention program only.

Conclusions.

In obese children with sHT dietary-behavioral management intervention contributed to reduction of body mass index, irrespective of levothyroxine use.

This finding suggests that moderately elevated levels of TSH are a consequence rather than cause of overweight and pharmacological treatment should be avoided.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Matusik, Pawel& Gawlik, Aneta& Januszek-Trzciakowska, Aleksandra& Malecka-Tendera, Ewa. 2015. Isolated Subclinical Hyperthyrotropinemia in Obese Children: Does Levothyroxine (LT4) Improve Weight Reduction during Combined Behavioral Therapy?. International Journal of Endocrinology،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1065813

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Matusik, Pawel…[et al.]. Isolated Subclinical Hyperthyrotropinemia in Obese Children: Does Levothyroxine (LT4) Improve Weight Reduction during Combined Behavioral Therapy?. International Journal of Endocrinology No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1065813

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Matusik, Pawel& Gawlik, Aneta& Januszek-Trzciakowska, Aleksandra& Malecka-Tendera, Ewa. Isolated Subclinical Hyperthyrotropinemia in Obese Children: Does Levothyroxine (LT4) Improve Weight Reduction during Combined Behavioral Therapy?. International Journal of Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1065813

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1065813