Reduced Representation Libraries from DNA Pools Analysed with Next Generation Semiconductor Based-Sequencing to Identify SNPs in Extreme and Divergent Pigs for Back Fat Thickness
المؤلفون المشاركون
Fontanesi, Luca
Dall'Olio, Stefania
Bovo, Samuele
Bertolini, Francesca
Schiavo, Giuseppina
Mazzoni, Gianluca
المصدر
International Journal of Genomics
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-04
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
The aim of this study was to identify single nucleotide polymorphisms (SNPs) that could be associated with back fat thickness (BFT) in pigs.
To achieve this goal, we evaluated the potential and limits of an experimental design that combined several methodologies.
DNA samples from two groups of Italian Large White pigs with divergent estimating breeding value (EBV) for BFT were separately pooled and sequenced, after preparation of reduced representation libraries (RRLs), on the Ion Torrent technology.
Taking advantage from SNAPE for SNPs calling in sequenced DNA pools, 39,165 SNPs were identified; 1/4 of them were novel variants not reported in dbSNP.
Combining sequencing data with Illumina PorcineSNP60 BeadChip genotyping results on the same animals, 661 genomic positions overlapped with a good approximation of minor allele frequency estimation.
A total of 54 SNPs showing enriched alleles in one or in the other RRLs might be potential markers associated with BFT.
Some of these SNPs were close to genes involved in obesity related phenotypes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bovo, Samuele& Bertolini, Francesca& Schiavo, Giuseppina& Mazzoni, Gianluca& Dall'Olio, Stefania& Fontanesi, Luca. 2015. Reduced Representation Libraries from DNA Pools Analysed with Next Generation Semiconductor Based-Sequencing to Identify SNPs in Extreme and Divergent Pigs for Back Fat Thickness. International Journal of Genomics،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1066050
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bovo, Samuele…[et al.]. Reduced Representation Libraries from DNA Pools Analysed with Next Generation Semiconductor Based-Sequencing to Identify SNPs in Extreme and Divergent Pigs for Back Fat Thickness. International Journal of Genomics No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1066050
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bovo, Samuele& Bertolini, Francesca& Schiavo, Giuseppina& Mazzoni, Gianluca& Dall'Olio, Stefania& Fontanesi, Luca. Reduced Representation Libraries from DNA Pools Analysed with Next Generation Semiconductor Based-Sequencing to Identify SNPs in Extreme and Divergent Pigs for Back Fat Thickness. International Journal of Genomics. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1066050
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1066050
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر