High Dose Dexmedetomidine: Effective as a Sole Agent Sedation for Children Undergoing MRI
المؤلفون المشاركون
Ahmed, Sheikh Sohail
Unland, Tamara
Slaven, James E.
Nitu, Mara E.
المصدر
International Journal of Pediatrics
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-01-29
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
To determine the efficacy and safety of high dose dexmedetomidine as a sole sedative agent for MRI.
We report our institution’s experience.
Design.
A retrospective institutional review of dexmedetomidine usage for pediatric MRI over 5.5 years.
Protocol included a dexmedetomidine bolus of 2 μg/kg intravenously over ten minutes followed by 1 μg/kg/hr infusion.
544 patients received high dose dexmedetomidine for MRI.
A second bolus was used in 103 (18.9%) patients.
117 (21.5%) required additional medications.
Efficacy, side effects, and use of additional medicines to complete the MRI were reviewed.
Data was analyzed using Student’s t-test, Fisher’s exact test, and Analysis of Variance (ANOVA).
Main Results.
Dexmedetomidine infusion was associated with bradycardia (3.9%) and hypotension (18.4%).
None of the patients required any intervention.
Vital signs were not significantly different among the subgroup of patients receiving one or two boluses of dexmedetomidine or additional medications.
Procedure time was significantly shorter in the group receiving only one dexmedetomidine bolus and increased with second bolus or additional medications ( P < 0.0001 ).
Discharge time was longer for children experiencing bradycardia ( P = 0.0012 ).
Conclusion.
High dose Dexmedetomidine was effective in 78.5% of cases; 21.5% of patients required additional medications.
Side effects occurred in approximately 25% of cases, resolving spontaneously.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ahmed, Sheikh Sohail& Unland, Tamara& Slaven, James E.& Nitu, Mara E.. 2015. High Dose Dexmedetomidine: Effective as a Sole Agent Sedation for Children Undergoing MRI. International Journal of Pediatrics،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1066698
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ahmed, Sheikh Sohail…[et al.]. High Dose Dexmedetomidine: Effective as a Sole Agent Sedation for Children Undergoing MRI. International Journal of Pediatrics No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1066698
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ahmed, Sheikh Sohail& Unland, Tamara& Slaven, James E.& Nitu, Mara E.. High Dose Dexmedetomidine: Effective as a Sole Agent Sedation for Children Undergoing MRI. International Journal of Pediatrics. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1066698
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1066698
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر