Evaluation of Microcrystalline Chitosan and Fibrin Membranes as Platelet-Derived Growth Factor-BB Carriers with Amoxicillin
المؤلفون المشاركون
Michalska, Marta
Bodek, Kazimiera H.
Nowak, Karolina M.
Kozakiewicz, Marcin
Bodek, Andrzej
المصدر
International Journal of Polymer Science
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-10-04
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
The aim of this study was to describe the mechanical and sorption features of homogeneous and composite membranes which consist of microcrystalline chitosan (MCCh) and fibrin (Fb) in various proportions as well as the in vitro kinetics of platelet-derived growth factor-BB (PDGF-BB) released from ten types of membranes in the presence or absence of amoxicillin (Am).
The films were characterized by Fourier transform infrared (FTIR) spectroscopy, mechanical tests: breaking strength (Bs) and elongation at break (Eb), as well as SEM images, and swelling study.
The influence of the form of samples (dry or wet) on Young’s modulus (E) was also examined.
The homogeneous MCCh (M1) and composite M3 and M4 (MCCh : Fb = 2 : 1 and 1 : 1) membranes were characterized by good sorption properties and higher mechanical strength, when compared with Fb (M2) membrane.
Connecting MCCh with Fb decreases release of PDGF-BB and increases release of Am.
The most efficient release of PDGF-BB was observed in the case of M4 (the optimum MCCh : Fb ratio was 1 : 1) membrane.
It was found that the degree of PDGF-BB release from the membrane is influenced by the physicochemical and mechanical characteristics of the films and by its affinity to growth factor PDGF-BB.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bodek, Kazimiera H.& Nowak, Karolina M.& Kozakiewicz, Marcin& Bodek, Andrzej& Michalska, Marta. 2015. Evaluation of Microcrystalline Chitosan and Fibrin Membranes as Platelet-Derived Growth Factor-BB Carriers with Amoxicillin. International Journal of Polymer Science،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1066768
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bodek, Kazimiera H.…[et al.]. Evaluation of Microcrystalline Chitosan and Fibrin Membranes as Platelet-Derived Growth Factor-BB Carriers with Amoxicillin. International Journal of Polymer Science No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1066768
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bodek, Kazimiera H.& Nowak, Karolina M.& Kozakiewicz, Marcin& Bodek, Andrzej& Michalska, Marta. Evaluation of Microcrystalline Chitosan and Fibrin Membranes as Platelet-Derived Growth Factor-BB Carriers with Amoxicillin. International Journal of Polymer Science. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1066768
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1066768
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر