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Solid-Phase Extraction of Pesticides by Using Bioinspired Peptide Receptors
المؤلفون المشاركون
Compagnone, Dario
Mascini, Marcello
Lanzone, Valentina
Scarpone, Rossana
Della Pelle, Flavio
Scortichini, Giampiero
Del Carlo, Michele
Sergi, Manuel
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-05-12
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
A virtual development of hexapeptide receptors bioinspired by the acetylcholinesterase enzyme active site is proposed.
A semicombinatorial approach was applied to generate a virtual hexapeptides library with different affinity properties towards organophosphate and carbamate pesticides.
The virtual screening process was addressed to obtain peptides able to separate pesticide subclasses in the experimental work.
Three hexapeptides, two generated by molecular modeling and one having a scrambled sequence, were used as selective sorbent materials for pesticides in preanalytical solid-phase extraction (SPE) method.
Selective adsorption and cross-reactivity were tested directly on a mix of four pesticides (carbaryl, chlorpyrifos-ethyl, malathion, and thiabendazole) having different structures and physico-chemical properties, at a total concentration of 120 ppb (each pesticide at concentration of 30 ppb).
The results were compared to traditional sorbent material such as C-18 and strata-X.
Data showed that only one of the hexapeptides virtually designed had significant differences in competitive absorption between aliphatic pesticide malathion, fungicide thiabendazole chosen as negative control, and aromatic pesticides.
These results partially supported the simulated strategy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lanzone, Valentina& Sergi, Manuel& Mascini, Marcello& Scarpone, Rossana& Della Pelle, Flavio& Del Carlo, Michele…[et al.]. 2015. Solid-Phase Extraction of Pesticides by Using Bioinspired Peptide Receptors. Journal of Chemistry،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1067677
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lanzone, Valentina…[et al.]. Solid-Phase Extraction of Pesticides by Using Bioinspired Peptide Receptors. Journal of Chemistry No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1067677
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lanzone, Valentina& Sergi, Manuel& Mascini, Marcello& Scarpone, Rossana& Della Pelle, Flavio& Del Carlo, Michele…[et al.]. Solid-Phase Extraction of Pesticides by Using Bioinspired Peptide Receptors. Journal of Chemistry. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1067677
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1067677
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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