Changes in Plasma Levels of N-Arachidonoyl Ethanolamine and N-Palmitoylethanolamine following Bariatric Surgery in Morbidly Obese Females with Impaired Glucose Homeostasis
المؤلفون المشاركون
Mallipedhi, Akhila
Prior, Sarah L.
Dunseath, Gareth
Bracken, Richard M.
Barry, Jonathan
Caplin, Scott
Eyre, Nia
Morgan, James
Baxter, John N.
O’Sullivan, Saoirse E.
Sarmad, Sarir
Barrett, David A.
Bain, Stephen C.
Luzio, Steve D.
Stephens, Jeffrey W.
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-22
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Aim.
We examined endocannabinoids (ECs) in relation to bariatric surgery and the association between plasma ECs and markers of insulin resistance.
Methods.
A study of 20 participants undergoing bariatric surgery.
Fasting and 2-hour plasma glucose, lipids, insulin, and C-peptide were recorded preoperatively and 6 months postoperatively with plasma ECs (AEA, 2-AG) and endocannabinoid-related lipids (PEA, OEA).
Results.
Gender-specific analysis showed differences in AEA, OEA, and PEA preoperatively with reductions in AEA and PEA in females postoperatively.
Preoperatively, AEA was correlated with 2-hour glucose (r=0.55, P=0.01), HOMA-IR (r=0.61, P=0.009), and HOMA %S (r=-0.71, P=0.002).
OEA was correlated with weight (r=0.49, P=0.03), waist circumference (r=0.52, P=0.02), fasting insulin (r=0.49, P=0.04), and HOMA-IR (r=0.48, P=0.05).
PEA was correlated with fasting insulin (r=0.49, P=0.04).
2-AG had a negative correlation with fasting glucose (r=-0.59, P=0.04).
Conclusion.
Gender differences exist in circulating ECs in obese subjects.
Females show changes in AEA and PEA after bariatric surgery.
Specific correlations exist between different ECs and markers of obesity and insulin and glucose homeostasis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mallipedhi, Akhila& Prior, Sarah L.& Dunseath, Gareth& Bracken, Richard M.& Barry, Jonathan& Caplin, Scott…[et al.]. 2015. Changes in Plasma Levels of N-Arachidonoyl Ethanolamine and N-Palmitoylethanolamine following Bariatric Surgery in Morbidly Obese Females with Impaired Glucose Homeostasis. Journal of Diabetes Research،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1067975
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mallipedhi, Akhila…[et al.]. Changes in Plasma Levels of N-Arachidonoyl Ethanolamine and N-Palmitoylethanolamine following Bariatric Surgery in Morbidly Obese Females with Impaired Glucose Homeostasis. Journal of Diabetes Research No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1067975
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mallipedhi, Akhila& Prior, Sarah L.& Dunseath, Gareth& Bracken, Richard M.& Barry, Jonathan& Caplin, Scott…[et al.]. Changes in Plasma Levels of N-Arachidonoyl Ethanolamine and N-Palmitoylethanolamine following Bariatric Surgery in Morbidly Obese Females with Impaired Glucose Homeostasis. Journal of Diabetes Research. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1067975
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1067975
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر