Edible Bird’s Nest Prevents High Fat Diet-Induced Insulin Resistance in Rats
المؤلفون المشاركون
Chan, Kim Wei
Imam, Mustapha Umar
Azmi, Nur Hanisah
Ismail, Maznah
Yida, Zhang
Ooi, Der-Jiun
Sarega, Nadarajan
Hou, Zhiping
Yusuf, Norhayati Binti
Ismail, Norsharina
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-07-27
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Edible bird’s nest (EBN) is used traditionally in many parts of Asia to improve wellbeing, but there are limited studies on its efficacy.
We explored the potential use of EBN for prevention of high fat diet- (HFD-) induced insulin resistance in rats.
HFD was given to rats with or without simvastatin or EBN for 12 weeks.
During the intervention period, weight measurements were recorded weekly.
Blood samples were collected at the end of the intervention and oral glucose tolerance test conducted, after which the rats were sacrificed and their liver and adipose tissues collected for further studies.
Serum adiponectin, leptin, F2-isoprostane, insulin, and lipid profile were estimated, and homeostatic model assessment of insulin resistance computed.
Effects of the different interventions on transcriptional regulation of insulin signaling genes were also evaluated.
The results showed that HFD worsened metabolic indices and induced insulin resistance partly through transcriptional regulation of the insulin signaling genes.
Additionally, simvastatin was able to prevent hypercholesterolemia but promoted insulin resistance similar to HFD.
EBN, on the other hand, prevented the worsening of metabolic indices and transcriptional changes in insulin signaling genes due to HFD.
The results suggest that EBN may be used as functional food to prevent insulin resistance.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yida, Zhang& Imam, Mustapha Umar& Ismail, Maznah& Ooi, Der-Jiun& Sarega, Nadarajan& Azmi, Nur Hanisah…[et al.]. 2015. Edible Bird’s Nest Prevents High Fat Diet-Induced Insulin Resistance in Rats. Journal of Diabetes Research،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1067996
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yida, Zhang…[et al.]. Edible Bird’s Nest Prevents High Fat Diet-Induced Insulin Resistance in Rats. Journal of Diabetes Research No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1067996
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yida, Zhang& Imam, Mustapha Umar& Ismail, Maznah& Ooi, Der-Jiun& Sarega, Nadarajan& Azmi, Nur Hanisah…[et al.]. Edible Bird’s Nest Prevents High Fat Diet-Induced Insulin Resistance in Rats. Journal of Diabetes Research. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1067996
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1067996
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر