Complexity and Controversies over the Cytokine Profiles of T Helper Cell Subpopulations in Tuberculosis
المؤلفون المشاركون
Vinícius da Silva, Marcos
de Oliveira, Carlo Jose Freire
Silva, Djalma A. A.
Tiburcio, Monique Gomes Salles
Rodrigues, Denise Bertulucci Rocha
Rodrigues, Virmondes
Machado, Juliana Reis
المصدر
Journal of Immunology Research
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-10-01
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Tuberculosis (TB) is a contagious infectious disease caused by the TB-causing bacillus Mycobacterium tuberculosis and is considered a public health problem with enormous social impact.
Disease progression is determined mainly by the balance between the microorganism and the host defense systems.
Although the immune system controls the infection, this control does not necessarily lead to sterilization.
Over recent decades, the patterns of CD4+ T cell responses have been studied with a goal of complete understanding of the immunological mechanisms involved in the maintenance of latent or active tuberculosis infection and of the clinical cure after treatment.
Conflicting results have been suggested over the years, particularly in studies comparing experimental models and human disease.
In recent years, in addition to Th1, Th2, and Th17 profiles, new standards of cellular immune responses, such as Th9, Th22, and IFN-γ-IL-10 double-producing Th cells, discussed here, have also been described.
Additionally, many new roles and cellular sources have been described for IL-10, demonstrating a critical role for this cytokine as regulatory, rather than merely pathogenic cytokine, involved in the establishment of chronic latent infection, in the clinical cure after treatment and in keeping antibacillary effector mechanisms active to prevent immune-mediated damage.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Vinícius da Silva, Marcos& Tiburcio, Monique Gomes Salles& Machado, Juliana Reis& Silva, Djalma A. A.& Rodrigues, Denise Bertulucci Rocha& Rodrigues, Virmondes…[et al.]. 2015. Complexity and Controversies over the Cytokine Profiles of T Helper Cell Subpopulations in Tuberculosis. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1068541
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Vinícius da Silva, Marcos…[et al.]. Complexity and Controversies over the Cytokine Profiles of T Helper Cell Subpopulations in Tuberculosis. Journal of Immunology Research No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1068541
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Vinícius da Silva, Marcos& Tiburcio, Monique Gomes Salles& Machado, Juliana Reis& Silva, Djalma A. A.& Rodrigues, Denise Bertulucci Rocha& Rodrigues, Virmondes…[et al.]. Complexity and Controversies over the Cytokine Profiles of T Helper Cell Subpopulations in Tuberculosis. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1068541
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1068541
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر