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Treatment of Thrombotic Antiphospholipid Syndrome: The Rationale of Current Management—An Insight into Future Approaches
المؤلفون المشاركون
Meroni, Pier-Luigi
Chighizola, Cecilia Beatrice
Ubiali, Tania
المصدر
Journal of Immunology Research
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-20، 20ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-05-05
دولة النشر
مصر
عدد الصفحات
20
التخصصات الرئيسية
الملخص EN
Vascular thrombosis and pregnancy morbidity represent the clinical manifestations of antiphospholipid syndrome (APS), which is serologically characterized by the persistent positivity of antiphospholipid antibodies (aPL).
Antiplatelet and anticoagulant agents currently provide the mainstay of APS treatment.
However, the debate is still open: controversies involve the intensity and the duration of anticoagulation and the treatment of stroke and refractory cases.
Unfortunately, the literature cannot provide definite answers to these controversial issues as it is flawed by many limitations, mainly due to the recruitment of patients not fulfilling laboratory and clinical criteria for APS.
The recommended therapeutic management of different aPL-related clinical manifestations is hereby presented, with a critical appraisal of the evidence supporting such approaches.
Cutting edge therapeutic strategies are also discussed, presenting the pioneer reports about the efficacy of novel pharmacological agents in APS.
Thanks to a better understanding of aPL pathogenic mechanisms, new therapeutic targets will soon be explored.
Much work is still to be done to unravel the most controversial issues about APS management: future studies are warranted to define the optimal management according to aPL risk profile and to assess the impact of a strict control of cardiovascular risk factors on disease control.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chighizola, Cecilia Beatrice& Ubiali, Tania& Meroni, Pier-Luigi. 2015. Treatment of Thrombotic Antiphospholipid Syndrome: The Rationale of Current Management—An Insight into Future Approaches. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-20.
https://search.emarefa.net/detail/BIM-1068650
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chighizola, Cecilia Beatrice…[et al.]. Treatment of Thrombotic Antiphospholipid Syndrome: The Rationale of Current Management—An Insight into Future Approaches. Journal of Immunology Research No. 2015 (2015), pp.1-20.
https://search.emarefa.net/detail/BIM-1068650
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chighizola, Cecilia Beatrice& Ubiali, Tania& Meroni, Pier-Luigi. Treatment of Thrombotic Antiphospholipid Syndrome: The Rationale of Current Management—An Insight into Future Approaches. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-20.
https://search.emarefa.net/detail/BIM-1068650
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1068650
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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