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Evaluation of Synthesized Nanohydroxyapatite-Nanocellulose Composites as Biocompatible Scaffolds for Applications in Bone Tissue Engineering
المؤلفون المشاركون
Herdocia-Lluberes, Claudia S.
Laboy-López, Simara
Morales, Stefannie
Gonzalez-Robles, Tania J.
González-Feliciano, José A.
Nicolau, Eduardo
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-27
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Basic calcium phosphate (BCP) crystals have been associated with many diseases due to their activation of signaling pathways that lead to their mineralization and deposition in intra-articular and periarticular locations in the bones.
In this study, hydroxyapatite (HAp) has been placed in a polysaccharide network as a strategy to minimize this deposition.
This research consisted of the evaluation of varying proportions of the polysaccharide network, cellulose nanocrystals (CNCs), and HAp synthesized via a simple sol-gel method.
The resulting biocompatible composites were extensively characterized by means of thermogravimetric analysis (TGA), powder X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), dynamic light scattering (DLS), zeta potential, and scanning electron microscopy (SEM).
It was found that an nHAp = CNC ratio presented greater homogeneity in the size and distribution of the nanoparticles without compromising the crystalline structure.
Also, incorporation of bone morphogenetic protein 2 (BMP-2) was performed to evaluate the effects that this interaction would have in the constructs.
Finally, the osteoblast cell (hFOB 1.19) viability assay was executed and it showed that all of the materials promoted greater cell proliferation while the nHAp > CNC proportion with the inclusion of the BMP-2 protein was the best composite for the purpose of this study.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Herdocia-Lluberes, Claudia S.& Laboy-López, Simara& Morales, Stefannie& Gonzalez-Robles, Tania J.& González-Feliciano, José A.& Nicolau, Eduardo. 2015. Evaluation of Synthesized Nanohydroxyapatite-Nanocellulose Composites as Biocompatible Scaffolds for Applications in Bone Tissue Engineering. Journal of Nanomaterials،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1068910
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Herdocia-Lluberes, Claudia S.…[et al.]. Evaluation of Synthesized Nanohydroxyapatite-Nanocellulose Composites as Biocompatible Scaffolds for Applications in Bone Tissue Engineering. Journal of Nanomaterials No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1068910
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Herdocia-Lluberes, Claudia S.& Laboy-López, Simara& Morales, Stefannie& Gonzalez-Robles, Tania J.& González-Feliciano, José A.& Nicolau, Eduardo. Evaluation of Synthesized Nanohydroxyapatite-Nanocellulose Composites as Biocompatible Scaffolds for Applications in Bone Tissue Engineering. Journal of Nanomaterials. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1068910
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1068910
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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