Stereotactic Radiosurgery for Renal Cancer Brain Metastasis: Prognostic Factors and the Role of Whole-Brain Radiation and Surgical Resection
المؤلفون المشاركون
Mahadevan, Anand
Ippen, Franziska M.
Wong, Eric T.
Uhlmann, Erik J.
Sengupta, Soma
Kasper, Ekkehard M.
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-11-19
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Background.
Renal cell carcinoma is a frequent source of brain metastasis.
We present our consecutive series of patients treated with Stereotactic Radiosurgery (SRS) and analyse prognostic factors and the interplay of WBRT and surgical resection.
Methods.
This is a retrospective study of 66 patients with 207 lesions treated with the Cyberknife radiosurgery system in our institution.
The patients were followed up with imaging and clinical examination 1 month and 2-3 months thereafter for the brain metastasis.
Patient, treatment, and outcomes characteristics were analysed.
Results.
51 male (77.3%) and 15 female (22.7%) patients, with a mean age of 58.9 years (range of 31–85 years) and a median Karnofsky Performance Status (KPS) of 90 (range of 60–100), were included in the study.
The overall survival was 13.9 months, 21.9 months, and 5.9 months for the patients treated with SRS only, additional surgery, and WBRT, respectively.
The actuarial 1-year Local Control rates were 84%, 94%, and 88% for SRS only, for surgery and SRS, and for WBRT and additional SRS, respectively.
Conclusions.
Stereotactic radiosurgery is a safe and effective treatment option in patients with brain metastases from RCC.
In case of a limited number of brain metastases, surgery and SRS might be appropriate.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ippen, Franziska M.& Mahadevan, Anand& Wong, Eric T.& Uhlmann, Erik J.& Sengupta, Soma& Kasper, Ekkehard M.. 2015. Stereotactic Radiosurgery for Renal Cancer Brain Metastasis: Prognostic Factors and the Role of Whole-Brain Radiation and Surgical Resection. Journal of Oncology،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1069580
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ippen, Franziska M.…[et al.]. Stereotactic Radiosurgery for Renal Cancer Brain Metastasis: Prognostic Factors and the Role of Whole-Brain Radiation and Surgical Resection. Journal of Oncology No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1069580
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ippen, Franziska M.& Mahadevan, Anand& Wong, Eric T.& Uhlmann, Erik J.& Sengupta, Soma& Kasper, Ekkehard M.. Stereotactic Radiosurgery for Renal Cancer Brain Metastasis: Prognostic Factors and the Role of Whole-Brain Radiation and Surgical Resection. Journal of Oncology. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1069580
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1069580
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر