An Additive Effect of Oral N-Acetyl Cysteine on Eradication of Helicobacter pylori
المؤلفون المشاركون
Hamidian, Seyed Mohammad-Taghi
Aletaha, Najmeh-sadat
Taslimi, Reza
Montazeri, Mohamad
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-09-02
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
Helicobacter pylori is highly adapted to the gastric environment where it lives within or beneath the gastric mucous layer.
The aim of this study was to evaluate whether the addition of N-acetyl cysteine to the treatment regimen of H.
pylori infection would affect eradication rates of the disease.
Methods.
A total of 79 H.
pylori positive patients were randomized to two therapeutic groups.
Both groups received a 14-day course of three-drug regimen including amoxicillin/clarithromycin/omeprazole.
Experimental group (38 subjects) received NAC, and control group (41 subjects) received placebo, besides three-drug regimen.
H.
pylori eradication was evaluated by urea breath test at least 4 weeks after the cessation of therapy.
Results.
The rate of H.
pylori eradication was 72.9% and 60.9% in experimental and control groups, respectively ( P = 0.005 ).
By logistic regression modeling, female gender (OR 3.68, 95% CI: 1.06–5.79; P = 0.040 ) and treatment including NAC (OR 1.88, 95% CI: 0.68–3.15; P = 0.021 ) were independent factors associated with H.
pylori eradication.
Conclusion.
The results of the present study show that NAC has an additive effect on the eradication rates of H.
pylori obtained with three-drug regimen and appears to be a promising means of eradicating H.
pylori infection.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hamidian, Seyed Mohammad-Taghi& Aletaha, Najmeh-sadat& Taslimi, Reza& Montazeri, Mohamad. 2015. An Additive Effect of Oral N-Acetyl Cysteine on Eradication of Helicobacter pylori. Journal of Pathogens،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1069945
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hamidian, Seyed Mohammad-Taghi…[et al.]. An Additive Effect of Oral N-Acetyl Cysteine on Eradication of Helicobacter pylori. Journal of Pathogens No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1069945
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hamidian, Seyed Mohammad-Taghi& Aletaha, Najmeh-sadat& Taslimi, Reza& Montazeri, Mohamad. An Additive Effect of Oral N-Acetyl Cysteine on Eradication of Helicobacter pylori. Journal of Pathogens. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1069945
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1069945
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر