Prevalence of Virulence Factors and Drug Resistance in Clinical Isolates of Enterococci: A Study from North India
المؤلفون المشاركون
Banerjee, Tuhina
Anupurba, Shampa
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-08-23
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Along with emergence of multidrug resistance, presence of several virulence factors in enterococci is an emerging concept.
This study was undertaken to determine the prevalence of various virulence factors phenotypically and genotypically in enterococci and study their association with multidrug resistance.
A total of 310 enterococcal isolates were studied, comprising 155 E.
faecium and 155 E.
faecalis.
Antimicrobial susceptibility testing was done by disc diffusion and agar dilution method.
Hemolysin, gelatinase, biofilm production, and haemagglutination were detected phenotypically and presence of virulence genes, namely, asa1, gelE, cylA, esp, and hyl, was detected by multiplex PCR.
Of the total, 47.41% isolates were high level gentamicin resistant (HLGRE) and 7.09% were vancomycin resistant (VRE).
All the virulence traits studied were found in varying proportions, with majority in E.
faecalis (p>0.05).
Strong biofilm producers possessed either asa1 or gelE gene.
gelE silent gene was detected in 41.37% (12/29).
However, increase in resistance was associated with significant decrease in expression or acquisition of virulence genes.
Further, acquisition of vancomycin resistance was the significant factor responsible for the loss of virulence traits.
Though it is presumed that increased drug resistance correlates with increased virulence, acquisition of vancomycin resistance might be responsible for reduced expression of virulence traits to meet the “biological cost” relating to VRE.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Banerjee, Tuhina& Anupurba, Shampa. 2015. Prevalence of Virulence Factors and Drug Resistance in Clinical Isolates of Enterococci: A Study from North India. Journal of Pathogens،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1069949
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Banerjee, Tuhina& Anupurba, Shampa. Prevalence of Virulence Factors and Drug Resistance in Clinical Isolates of Enterococci: A Study from North India. Journal of Pathogens No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1069949
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Banerjee, Tuhina& Anupurba, Shampa. Prevalence of Virulence Factors and Drug Resistance in Clinical Isolates of Enterococci: A Study from North India. Journal of Pathogens. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1069949
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1069949
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر