Endemicity of Acinetobacter calcoaceticus-baumannii Complex in an Intensive Care Unit in Malaysia
المؤلفون المشاركون
Thong, Kwai-Lin
Dhanoa, Amreeta
Rajasekaram, Ganeswrie
Lean, Soo Sum
Cheong, Yuet Meng
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-27
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Introduction.
Acinetobacter calcoaceticus-baumannii complex (ACB complex) is a leading opportunistic pathogen in intensive care units (ICUs).
Effective control of spread requires understanding of its epidemiological relatedness.
This study aims to determine the genetic relatedness and antibiotic susceptibilities of ACB complex in an ICU in Malaysia.
Methodology.
Pulsed field gel electrophoresis (PFGE), E-test, and disk diffusion were used for isolates characterization.
Results.
During the study period (December 2011 to June 2012), 1023 patients were admitted to the ICU and 44 ACB complex (blood, n = 21 , and blind bronchial aspirates, n = 23 ) were recovered from 38 ICU patients.
Six isolates were from non-ICU patients.
Of the 44 ICU isolates, 88.6% exhibited multidrug-resistant (MDR) patterns.
There was high degree of resistance, with minimum inhibitory concentration90 (MIC90) of >32 μg/mL for carbapenems and ≥256 μg/mL for amikacin, ampicillin/sulbactam, and cefoperazone/sulbactam.
Isolates from the main PFGE cluster were highly resistant.
There was evidence of dissemination in non-ICU wards.
Conclusion.
High number of clonally related MDR ACB complex was found.
While the ICU is a likely reservoir facilitating transmission, importation from other wards may be important contributor.
Early identification of strain relatedness and implementation of infection control measures are necessary to prevent further spread.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dhanoa, Amreeta& Rajasekaram, Ganeswrie& Lean, Soo Sum& Cheong, Yuet Meng& Thong, Kwai-Lin. 2015. Endemicity of Acinetobacter calcoaceticus-baumannii Complex in an Intensive Care Unit in Malaysia. Journal of Pathogens،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1069952
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dhanoa, Amreeta…[et al.]. Endemicity of Acinetobacter calcoaceticus-baumannii Complex in an Intensive Care Unit in Malaysia. Journal of Pathogens No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1069952
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dhanoa, Amreeta& Rajasekaram, Ganeswrie& Lean, Soo Sum& Cheong, Yuet Meng& Thong, Kwai-Lin. Endemicity of Acinetobacter calcoaceticus-baumannii Complex in an Intensive Care Unit in Malaysia. Journal of Pathogens. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1069952
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1069952
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر