Micellar Enhanced Three-Dimensional Excitation-Emission Matrix Fluorescence for Rapid Determination of Antihypertensives in Human Plasma with Aid of Second-Order Calibration Methods
المؤلفون المشاركون
Fu, Hai-Yan
She, Yuan-Bin
Fan, Yao
Yang, Tianming
Li, He-Dong
Ni, Chuang
Zhang, Hao
Yang, Ji
Chen, Lin
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-08-23
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
A highly sensitive three-dimensional excitation-emission fluorescence method was proposed to determine antihypertensives including valsartan and amlodipine besylate in human plasma with the aid of second-order calibration methods based on parallel factor analysis (PARAFAC) and alternating trilinear decomposition (ATLD) algorithms.
Antihypertensives with weak fluorescent can be transformed into a strong fluorescent property by changing microenvironment in samples using micellar enhanced surfactant.
Both the adopted algorithms with second-order advantage can improve the resolution and directly attain antihypertensives concentration even in the presence of potential strong intrinsic fluorescence from human plasma.
The satisfactory results can be achieved for valsartan and amlodipine besylate in complicated human plasma.
Furthermore, some statistical parameters and figures of merit were evaluated to investigate the performance of the proposed method, and the accuracy and precision of the proposed method were also validated by the elliptical joint confidence region (EJCR) test and repeatability analysis of intraday and interday assay.
The proposed method could not only light a new avenue to directly determine valsartan or amlodipine besylate in human plasma, but also hold great potential to be extended as a promising alternative for more practical applications in the determination of weak fluorescent drugs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fu, Hai-Yan& Li, He-Dong& Ni, Chuang& Yang, Tianming& Fan, Yao& Zhang, Hao…[et al.]. 2015. Micellar Enhanced Three-Dimensional Excitation-Emission Matrix Fluorescence for Rapid Determination of Antihypertensives in Human Plasma with Aid of Second-Order Calibration Methods. Journal of Spectroscopy،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1070328
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fu, Hai-Yan…[et al.]. Micellar Enhanced Three-Dimensional Excitation-Emission Matrix Fluorescence for Rapid Determination of Antihypertensives in Human Plasma with Aid of Second-Order Calibration Methods. Journal of Spectroscopy No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1070328
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fu, Hai-Yan& Li, He-Dong& Ni, Chuang& Yang, Tianming& Fan, Yao& Zhang, Hao…[et al.]. Micellar Enhanced Three-Dimensional Excitation-Emission Matrix Fluorescence for Rapid Determination of Antihypertensives in Human Plasma with Aid of Second-Order Calibration Methods. Journal of Spectroscopy. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1070328
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1070328
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر