Early Dynamics of Cerebrospinal CD14+ Monocytes and CD15+ Granulocytes in Patients after Severe Traumatic Brain Injury: A Cohort Study
المؤلفون المشاركون
van Griensven, Martijn
Biberthaler, P.
Bogner, V.
Postl, Lukas Kurt
Beirer, Marc
Kanz, Karl Georg
Egginger, Christoph
Schmitt-Sody, Markus
Kirchhoff, Chlodwig
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-10-19
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
In traumatic brain injury (TBI) the analysis of neuroinflammatory mechanisms gained increasing interest.
In this context certain immunocompetent cells might play an important role.
Interestingly, in the actual literature there exist only a few studies focusing on the role of monocytes and granulocytes in TBI patients.
In this regard it has recently reported that the choroid plexus represents an early, selective barrier for leukocytes after brain injury.
Therefore the aim of this study was to evaluate the very early dynamics of CD14+ monocytes and CD15+ granulocyte in CSF of patients following severe TBI with regard to the integrity of the BBB.
Cytometric flow analysis was performed to analyze the CD14+ monocyte and CD15+ granulocyte population in CSF of TBI patients.
The ratio of CSF and serum albumin as a measure for the BBB’s integrity was assessed in parallel.
CSF samples of patients receiving lumbar puncture for elective surgery were obtained as controls.
Overall 15 patients following severe TBI were enrolled.
10 patients were examined as controls.
In patients, the monocyte population as well as the granulocyte population was significantly increased within 72 hours after TBI.
The BBB’s integrity did not have a significant influence on the cell count in the CSF.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Postl, Lukas Kurt& Bogner, V.& van Griensven, Martijn& Beirer, Marc& Kanz, Karl Georg& Egginger, Christoph…[et al.]. 2015. Early Dynamics of Cerebrospinal CD14+ Monocytes and CD15+ Granulocytes in Patients after Severe Traumatic Brain Injury: A Cohort Study. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1072179
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Postl, Lukas Kurt…[et al.]. Early Dynamics of Cerebrospinal CD14+ Monocytes and CD15+ Granulocytes in Patients after Severe Traumatic Brain Injury: A Cohort Study. Mediators of Inflammation No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1072179
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Postl, Lukas Kurt& Bogner, V.& van Griensven, Martijn& Beirer, Marc& Kanz, Karl Georg& Egginger, Christoph…[et al.]. Early Dynamics of Cerebrospinal CD14+ Monocytes and CD15+ Granulocytes in Patients after Severe Traumatic Brain Injury: A Cohort Study. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1072179
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1072179
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر