Gender-Specific Association of Oxidative Stress and Inflammation with Cardiovascular Risk Factors in Arab Population
المؤلفون المشاركون
Dehbi, Mohammed
Tiss, Ali
Khadir, Abdelkrim
Kavalakatt, Sina
Elkum, Naser
Behbehani, Kazem
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-31
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Background.
The impact of gender difference on the association between metabolic stress and cardiovascular disease (CVD) remains unclear.
We have investigated, for the first time, the gender effect on the oxidative and inflammatory stress responses and assessed their correlation with classical cardiometabolites in Arab population.
Methods.
A total of 378 adult Arab participants (193 females) were enrolled in this cross-sectional study.
Plasma levels of CRP, IL-6, IL-8, TNF-α, ROS, TBARs, and PON1 were measured and correlated with anthropometric and cardiometabolite parameters of the study population.
Results.
Compared to females, males had significantly higher FBG, HbA1c, TG, and blood pressure but lower BMI, TC, and HDL (P < 0.05).
After adjustment for BMI and WC, females had higher levels of ROS, TBARS, and CRP (P < 0.001) whereas males had increased levels of IL-8, IL-6, and TNF-α (P < 0.05).
Moreover, after adjustment for age, BMI, and gender, the levels of TNF-α, IL-6, and ROS were associated with central obesity but not general obesity.
Conclusion.
Inflammation and oxidative stress contribution to CVD risk in Arab population linked to gender and this risk is better reflected by central obesity.
Arab females might be at risk of CVD complications due to increased oxidative stress.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Khadir, Abdelkrim& Tiss, Ali& Kavalakatt, Sina& Behbehani, Kazem& Dehbi, Mohammed& Elkum, Naser. 2015. Gender-Specific Association of Oxidative Stress and Inflammation with Cardiovascular Risk Factors in Arab Population. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1072396
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Khadir, Abdelkrim…[et al.]. Gender-Specific Association of Oxidative Stress and Inflammation with Cardiovascular Risk Factors in Arab Population. Mediators of Inflammation No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1072396
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Khadir, Abdelkrim& Tiss, Ali& Kavalakatt, Sina& Behbehani, Kazem& Dehbi, Mohammed& Elkum, Naser. Gender-Specific Association of Oxidative Stress and Inflammation with Cardiovascular Risk Factors in Arab Population. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1072396
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1072396
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر