Expression of Toll-Like Receptors 2 and 4 and Related Cytokines in Patients with Hepatic Cystic and Alveolar Echinococcosis
المؤلفون المشاركون
Tuxun, Tuerhongjiang
Apaer, Shadike
Zhang, Heng
Ma, Hai-Zhang
Aierken, Amina
Li, Yu-Peng
Lin, Ren-Yong
Zhao, Jin-Ming
Zhang, Jin-Hui
Wen, Hao
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-11-09
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Several studies have demonstrated the important role of Toll-like receptors in various parasitic infections.
This study aims to explore expression of Toll-like receptors (TLRs) and related cytokines in patients with human cystic echinococcosis (CE) and alveolar echinococcosis (AE).
78 subjects including AE group ( N = 28 ), CE group ( N = 22 ), and healthy controls (HC, N = 28 ) were enrolled in this study.
The mRNA expression levels of TLR2 and TLR4 in blood and hepatic tissue and plasma levels related cytokines were detected by using ELISA.
Median levels of TLR2 mRNA in AE and CE groups were significantly elevated as compared with that in healthy control group.
Median levels of TLR4 expression were increased in AE and CE.
Plasma concentration levels of IL-5, IL-6, and IL-10 were slightly increased in AE and CE groups compared with those in HC group with no statistical differences ( p > 0.05 ).
The IL-23 concentration levels were significantly higher in AE and CE groups than that in HC subjects with statistical significance.
The increased expression of TLR2 and IL-23 might play a potential role in modulating tissue infiltrative growth of the parasite and its persistence in the human host.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tuxun, Tuerhongjiang& Ma, Hai-Zhang& Apaer, Shadike& Zhang, Heng& Aierken, Amina& Li, Yu-Peng…[et al.]. 2015. Expression of Toll-Like Receptors 2 and 4 and Related Cytokines in Patients with Hepatic Cystic and Alveolar Echinococcosis. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1072475
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tuxun, Tuerhongjiang…[et al.]. Expression of Toll-Like Receptors 2 and 4 and Related Cytokines in Patients with Hepatic Cystic and Alveolar Echinococcosis. Mediators of Inflammation No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1072475
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tuxun, Tuerhongjiang& Ma, Hai-Zhang& Apaer, Shadike& Zhang, Heng& Aierken, Amina& Li, Yu-Peng…[et al.]. Expression of Toll-Like Receptors 2 and 4 and Related Cytokines in Patients with Hepatic Cystic and Alveolar Echinococcosis. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1072475
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1072475
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر