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Contralateral Metabolic Activation Related to Plastic Changes in the Spinal Cord after Peripheral Nerve Injury in Rats
المؤلفون المشاركون
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-09-28
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
We have previously reported the crossed-withdrawal reflex in which the rats with nerve injury developed behavioral pain responses of the injured paw to stimuli applied to the contralateral uninjured paw.
This reflex indicates that contralateral plastic changes may occur in the spinal cord after unilateral nerve injury.
The present study was performed to elucidate the mechanisms and morphological correlates underlying the crossed-withdrawal reflex by using quantitative 14C-2-deoxyglucose (2-DG) autoradiography which can examine metabolic activities and spatial patterns simultaneously.
Under pentobarbital anesthesia, rats were subjected to unilateral nerve injury.
Mechanical allodynia was tested for two weeks after nerve injury.
After nerve injury, neuropathic pain behaviors developed progressively.
The crossed-withdrawal reflex was observed at two weeks postoperatively.
Contralateral enhancement of 2-DG uptake in the ventral horn of the spinal cord to electrical stimulation of the uninjured paw was observed.
These results suggest that the facilitation of information processing from the uninjured side to the injured side may contribute to the crossed-withdrawal reflex by plastic changes in the spinal cord of nerve-injured rats.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Won, Ran& Lee, Bae Hwan. 2015. Contralateral Metabolic Activation Related to Plastic Changes in the Spinal Cord after Peripheral Nerve Injury in Rats. Neural Plasticity،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1075347
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Won, Ran& Lee, Bae Hwan. Contralateral Metabolic Activation Related to Plastic Changes in the Spinal Cord after Peripheral Nerve Injury in Rats. Neural Plasticity No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1075347
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Won, Ran& Lee, Bae Hwan. Contralateral Metabolic Activation Related to Plastic Changes in the Spinal Cord after Peripheral Nerve Injury in Rats. Neural Plasticity. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1075347
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1075347
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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