Placental Oxidative Status throughout Normal Gestation in Women with Uncomplicated Pregnancies
المؤلفون المشاركون
Bendek, Boleslaw
Agamasu, Enyonam
Mikhail, Magdy
Basu, Jayasri
Mishra, Aruna
Benfield, Nerys
Patel, Ronak
Salafia, Caroline
المصدر
Obstetrics and Gynecology International
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-02-01
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
The effects of gestational age on placental oxidative balance throughout gestation were investigated in women with uncomplicated pregnancies.
Placental tissues were obtained from normal pregnant women who delivered at term or underwent elective pregnancy termination at 6 to 23 + 6 weeks of pregnancy.
Placental tissues were analyzed for total antioxidant capacity (TAC) and lipid peroxide (malondialdehyde, MDA) levels using commercially available kits.
Two hundred and one placental tissues were analyzed and the mean ± SD MDA (pmol/mg tissue) and TAC (µmol Trolox equivalent/mg tissue) levels for first, second, and third trimester groups were 277.01 ± 204.66, 202.66 ± 185.05, and 176.97 ± 141.61, P < 0.004 and 498.62 ± 400.74, 454.90 ± 374.44, and 912.19 ± 586.21, P < 0.0001 by ANOVA, respectively.
Our data reflects an increased oxidative stress in the placenta in the early phase of normal pregnancy.
As pregnancy progressed, placental antioxidant protective mechanisms increased and lipid peroxidation markers decreased resulting in diminution in oxidative stress.
Our findings provide a biochemical support to the concept of a hypoxic environment in early pregnancy.
A decrease in placental oxidative stress in the second and third trimesters appears to be a physiological phenomenon of normal pregnancy.
Deviations from this physiological phenomenon may result in placental-mediated disorders.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Basu, Jayasri& Bendek, Boleslaw& Agamasu, Enyonam& Salafia, Caroline& Mishra, Aruna& Benfield, Nerys…[et al.]. 2015. Placental Oxidative Status throughout Normal Gestation in Women with Uncomplicated Pregnancies. Obstetrics and Gynecology International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1075494
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Basu, Jayasri…[et al.]. Placental Oxidative Status throughout Normal Gestation in Women with Uncomplicated Pregnancies. Obstetrics and Gynecology International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1075494
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Basu, Jayasri& Bendek, Boleslaw& Agamasu, Enyonam& Salafia, Caroline& Mishra, Aruna& Benfield, Nerys…[et al.]. Placental Oxidative Status throughout Normal Gestation in Women with Uncomplicated Pregnancies. Obstetrics and Gynecology International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1075494
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1075494
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر