Plasma Prolidase Activity and Oxidative Stress in Patients with Parkinson’s Disease
المؤلفون المشاركون
Verma, Akhilesh Kumar
Singh, Tej Bali
Srivastava, Ragini
Raj, Janak
Sharma, Vivek
Srivastava, Shalabh
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-08-09
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Prolidase deficiency has been related to mental retardation and oxidative stress.
The study aimed to observe plasma prolidase activity (PPA), total oxidant status (TOS), total antioxidant status (TAS), and oxidative stress index (OSI) in patients with Parkinson’s disease (PD).
240 subjects with PD and 150 healthy volunteers were considered as cases and controls, respectively.
PPA, TOS, TAS, and OSI were measured spectrophotometrically.
PPA and TAS in cases were more significantly decreased than controls (P<0.01), while TOS and OSI were significantly increased (P<0.001).
In cases, nonsignificant, positive correlation was observed between PPA and TOS and OSI while significant, negative correlation was observed between PPA and TAS (P=0.047).
PPA in cases was nonsignificantly decreased with increased duration of PD (P=0.747) while TAS was significantly decreased (P<0.001) and TOS and OSI were significantly increased (P<0.001).
It was observed that higher age groups had decreased PPA, and TAS and increased TOS and OSI compared to lower age groups in cases.
In summary, patients with PD have decreased PPA and increased oxidative stress compared to healthy volunteers.
PPA was associated with oxidative stress markers in patients with PD.
Decreased PPA and TAS and increased TOS and OSI were associated with progression of disease and higher age.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Verma, Akhilesh Kumar& Raj, Janak& Sharma, Vivek& Singh, Tej Bali& Srivastava, Shalabh& Srivastava, Ragini. 2015. Plasma Prolidase Activity and Oxidative Stress in Patients with Parkinson’s Disease. Parkinson’s Disease،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1075901
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Verma, Akhilesh Kumar…[et al.]. Plasma Prolidase Activity and Oxidative Stress in Patients with Parkinson’s Disease. Parkinson’s Disease No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1075901
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Verma, Akhilesh Kumar& Raj, Janak& Sharma, Vivek& Singh, Tej Bali& Srivastava, Shalabh& Srivastava, Ragini. Plasma Prolidase Activity and Oxidative Stress in Patients with Parkinson’s Disease. Parkinson’s Disease. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1075901
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1075901
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر