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Occurring of In Vitro Functional Vasculogenic Pericytes from Human Circulating Early Endothelial Precursor Cell Culture
المؤلفون المشاركون
Cantoni, Silvia
Bianchi, Francesca
Galletti, Margherita
Olivi, Elena
Alviano, Francesco
Galiè, Nazzareno
Ventura, Carlo
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-05-06
دولة النشر
مصر
عدد الصفحات
11
الملخص EN
Pericytes are periendothelial cells of the microcirculation which contribute to tissue homeostasis and hemostasis by regulating microvascular morphogenesis and stability.
Because of their multipotential ex vivo differentiation capabilities, pericytes are becoming very interesting in regenerative medicine field.
Several studies address this issue by attempting to isolate pericyte/mesenchymal-like cells from peripheral blood; however the origin of these cells and their culture conditions are still debated.
Here we showed that early Endothelial Progenitor Cells (EPCs) expressing CD45+/CD146+/CD31+ can be a source of cells with pericyte/mesenchymal phenotype and function, identified as human Progenitor Perivascular Cells (hPPCs).
We provided evidence that hPPCs have an immunophenotype consistent with Mesenchymal Stem Cells (MSCs) from human adipose tissue (hASCs) and fetal membranes of term placenta (FM-hMSCs).
In addition, hPPCs can be subcultured and exhibit expression of pluripotent genes (OCT-4, KLF-4, and NANOG) as well as a remarkable vasculogenic potential.
Our findings could be helpful to develop innovative cell-based therapies for future clinical applications with distinct therapeutic purposes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cantoni, Silvia& Bianchi, Francesca& Galletti, Margherita& Olivi, Elena& Alviano, Francesco& Galiè, Nazzareno…[et al.]. 2015. Occurring of In Vitro Functional Vasculogenic Pericytes from Human Circulating Early Endothelial Precursor Cell Culture. Stem Cells International،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1076389
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cantoni, Silvia…[et al.]. Occurring of In Vitro Functional Vasculogenic Pericytes from Human Circulating Early Endothelial Precursor Cell Culture. Stem Cells International No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1076389
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cantoni, Silvia& Bianchi, Francesca& Galletti, Margherita& Olivi, Elena& Alviano, Francesco& Galiè, Nazzareno…[et al.]. Occurring of In Vitro Functional Vasculogenic Pericytes from Human Circulating Early Endothelial Precursor Cell Culture. Stem Cells International. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1076389
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1076389
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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