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Hydrogels and Cell Based Therapies in Spinal Cord Injury Regeneration
المؤلفون المشاركون
Assunção-Silva, Rita C.
Gomes, Eduardo D.
Silva, Nuno A.
Sousa, Nuno
Salgado, Antonio
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-24، 24ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-06-01
دولة النشر
مصر
عدد الصفحات
24
الملخص EN
Spinal cord injury (SCI) is a central nervous system- (CNS-) related disorder for which there is yet no successful treatment.
Within the past several years, cell-based therapies have been explored for SCI repair, including the use of pluripotent human stem cells, and a number of adult-derived stem and mature cells such as mesenchymal stem cells, olfactory ensheathing cells, and Schwann cells.
Although promising, cell transplantation is often overturned by the poor cell survival in the treatment of spinal cord injuries.
Alternatively, the therapeutic role of different cells has been used in tissue engineering approaches by engrafting cells with biomaterials.
The latter have the advantages of physically mimicking the CNS tissue, while promoting a more permissive environment for cell survival, growth, and differentiation.
The roles of both cell- and biomaterial-based therapies as single therapeutic approaches for SCI repair will be discussed in this review.
Moreover, as the multifactorial inhibitory environment of a SCI suggests that combinatorial approaches would be more effective, the importance of using biomaterials as cell carriers will be herein highlighted, as well as the recent advances and achievements of these promising tools for neural tissue regeneration.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Assunção-Silva, Rita C.& Gomes, Eduardo D.& Sousa, Nuno& Silva, Nuno A.& Salgado, Antonio. 2015. Hydrogels and Cell Based Therapies in Spinal Cord Injury Regeneration. Stem Cells International،Vol. 2015, no. 2015, pp.1-24.
https://search.emarefa.net/detail/BIM-1076391
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Assunção-Silva, Rita C.…[et al.]. Hydrogels and Cell Based Therapies in Spinal Cord Injury Regeneration. Stem Cells International No. 2015 (2015), pp.1-24.
https://search.emarefa.net/detail/BIM-1076391
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Assunção-Silva, Rita C.& Gomes, Eduardo D.& Sousa, Nuno& Silva, Nuno A.& Salgado, Antonio. Hydrogels and Cell Based Therapies in Spinal Cord Injury Regeneration. Stem Cells International. 2015. Vol. 2015, no. 2015, pp.1-24.
https://search.emarefa.net/detail/BIM-1076391
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1076391
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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