Arginine Adjunctive Therapy in Active Tuberculosis
المؤلفون المشاركون
Farazi, Ali Asghar
Sofian, Masoomeh
Shafaat, Omid
Kahbazi, Manijeh
المصدر
Tuberculosis Research and Treatment
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-02-03
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
Dietary supplementation has been used as a mechanism to augment the immune system.
Adjunctive therapy with L-arginine has the potential to improve outcomes in active tuberculosis.
Methods.
In a randomized clinical trial 63 participants with smear-positive pulmonary tuberculosis in Markazi Province of Iran were given arginine or placebo for 4 weeks in addition to conventional chemotherapy.
The final treatment success, sputum conversion, weight gain, and clinical symptoms after one and two months were considered as primary outcomes and secondary outcomes were ESR, CRP, and Hg.
Data were collected and analyzed with SPSS software (ver.
18).
Results.
Arginine supplementation reduced constitutional symptoms (P=0.032) in patients with smear-positive TB at the end of the first month of treatment.
Arginine treated patients had significantly increased BMI at the end of the first and second months of treatment (P=0.032 and P=0.04) and a reduced CRP at the end of the first month of treatment (P=0.03) versus placebo group.
Conclusion.
Arginine is useful as an adjunctive therapy in patients with active tuberculosis, in which the effects are more likely mediated by the increased production of nitric oxide and improved constitutional symptoms and weight gain.
This trial is registered with Clinical Trials Registry of Iran: IRCT201211179855N2.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Farazi, Ali Asghar& Shafaat, Omid& Sofian, Masoomeh& Kahbazi, Manijeh. 2015. Arginine Adjunctive Therapy in Active Tuberculosis. Tuberculosis Research and Treatment،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1078431
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Farazi, Ali Asghar…[et al.]. Arginine Adjunctive Therapy in Active Tuberculosis. Tuberculosis Research and Treatment No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1078431
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Farazi, Ali Asghar& Shafaat, Omid& Sofian, Masoomeh& Kahbazi, Manijeh. Arginine Adjunctive Therapy in Active Tuberculosis. Tuberculosis Research and Treatment. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1078431
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1078431
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر