Prevalence of Tuberculosis, Drug Susceptibility Testing, and Genotyping of Mycobacterial Isolates from Pulmonary Tuberculosis Patients in Dessie, Ethiopia
المؤلفون المشاركون
Maru, Minwuyelet
Mariam, Solomon H.
Airgecho, Tekle
Gadissa, Endalamaw
Aseffa, Abraham
المصدر
Tuberculosis Research and Treatment
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-06-09
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Due to their initially seemingly high cost, timely diagnosis and effective treatment of tuberculosis (TB) are usually hampered by lack or shortage of resources in many high TB burden countries.
However, the benefits of effective treatment can eventually outweigh those of empirical treatment.
Here, a cross-sectional study was conducted on samples from smear-positive new and retreatment TB patients.
Data on sociodemographic and HIV status were collected.
Samples were cultured for identification, conventional drug sensitivity testing, and molecular typing by deletion typing and spoligotyping.
The results showed the youth were disproportionately affected.
New cases were being treated following general treatment guidelines only.
Monoresistance or multiple drug resistance was found in 16.5% of new patients.
Spoligotyping showed that there were 44 patterns with families H3 and T1 (lineage 4) and CAS-Delhi (lineage 3) being dominant.
Some rare patterns from lineage 7 were also found.
Spoligotype pattern, HIV positivity, and previous treatment were not associated with drug resistance.
That the vast majority of the patients were new cases and young and the large number of these patients with mono- or multiple drug resistance indicate that most TB cases are due to recent transmissions and that urgent actions are needed to curb the transmissions.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Maru, Minwuyelet& Mariam, Solomon H.& Airgecho, Tekle& Gadissa, Endalamaw& Aseffa, Abraham. 2015. Prevalence of Tuberculosis, Drug Susceptibility Testing, and Genotyping of Mycobacterial Isolates from Pulmonary Tuberculosis Patients in Dessie, Ethiopia. Tuberculosis Research and Treatment،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1078432
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Maru, Minwuyelet…[et al.]. Prevalence of Tuberculosis, Drug Susceptibility Testing, and Genotyping of Mycobacterial Isolates from Pulmonary Tuberculosis Patients in Dessie, Ethiopia. Tuberculosis Research and Treatment No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1078432
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Maru, Minwuyelet& Mariam, Solomon H.& Airgecho, Tekle& Gadissa, Endalamaw& Aseffa, Abraham. Prevalence of Tuberculosis, Drug Susceptibility Testing, and Genotyping of Mycobacterial Isolates from Pulmonary Tuberculosis Patients in Dessie, Ethiopia. Tuberculosis Research and Treatment. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1078432
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1078432
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر